UPCR

UPCR Calculator

Urine Protein-to-Creatinine Ratio

Urine Chemistry

Urine Total Protein (mg/dL)

Urine Creatinine (mg/dL)

Standardized for glomerular disease monitoring.

Protein Estimation

Enter urine protein and creatinine levels to estimate 24-hour excretion.

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

Initial screening and quantification of proteinuria in suspected glomerular or tubulointerstitial disease.

Monitoring disease activity in known nephropathies (e.g., Lupus Nephritis, Diabetic Nephropathy).

Evaluating for nephrotic-range proteinuria when a 24-hour urine collection is impractical.

Assessment of proteinuria in pregnancy (e.g., screening for Preeclampsia).

Clinical Objective

UPCR serves as a reliable surrogate for 24-hour urine protein excretion, normalizing protein loss to creatinine excretion to account for variations in urine concentration.

Related Scores in Practice

In clinical practice, this assessment is frequently evaluated alongside other validated measures. Depending on the patient's presentation and specific diagnostic requirements, you may also need to utilize the UACR, Egfr Calc, CKD Stage (KDIGO) or the Kfre Calc to formulate a comprehensive care plan.

Last Comprehensive Review: 2026

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FEUrea

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KFRE — Kidney Failure Risk

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