KFRE — Kidney Failure Risk

The KFRE was developed by Dr. Navdeep Tangri at Tufts Medical Center, USA, and first published in JAMA in 2011. Tangri recognised that nephrologists needed an individualised, probabilistic risk tool analogous to the Framingham Risk Score for cardiovascular disease — one that could move CKD management from reactive to proactive.

Since its publication, the KFRE has been embedded into electronic health records in Canada, Australia, and increasingly across Europe. It has been shown to change clinical management decisions in over 40% of cases where it is actively used.