OpiCalc

Favorites Specialties Drugs Guidelines Most Used

All Specialties

Favorites Specialties Drugs Guidelines Most Used

Faves Specs Drugs Guides Top

AKI Staging (KDIGO)Anion Gap + Delta-Delta CKD Stage (KDIGO)Creatinine Clearance Electrolyte & Free Water FENa FEUrea KFRE — Kidney Failure Risk Kt/V Dialysis Sodium Correction UACR UPCR Urea Reduction Ratio (URR) Calculator Uric Acid & FEUA Urinary Anion Gap Winter's Formula eGFR (CKD-EPI)

OpiCalc

Easy, fast, and private medical tools for clinicians. Always free.

No Login Required

Ready for the Bedside

Resources

About Us Editorial Policy Medical Disclaimer Privacy Policy Terms of Use Cookie Policy

Support

Clinical Notice:OpiCalc is not a substitute for professional clinical judgment. Always verify dosages and guidelines.

OpiCalc © 2018-2026

•

All Rights Reserved

In Recent Clinical News

Scanning Medical Journals

No new significant updates or guidelines matching this topic were found today. We will check again soon.

KFRE — Kidney Failure Risk

KFRE Calculator

Kidney Failure Risk Equation

Laboratory Input

Patient Age (Years)

eGFR (mL/min/1.73m²)

UACR (mg/g)

Biological Sex

KFRE is validated for patients with CKD Stage 3-5.

Progression Modeler

Enter laboratory metrics to execute high-fidelity kidney failure forecasting.

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

When to Use

CKD Stage G3a–G5 patients to estimate 2- and 5-year risk of kidney failure requiring Renal Replacement Therapy (RRT).

Timing of nephrology referral — KDIGO recommends referral when 5-year risk > 3–5%.

Planning for vascular access creation (fistula/graft) or peritoneal dialysis catheter placement.

Shared decision-making conversations about conservative vs. RRT management options.

Prioritising transplant evaluation workup in high-risk patients.

Required Variables (4-variable model)

Age (years)

Sex (biological)

eGFR (CKD-EPI, mL/min/1.73m2)

UACR (mg/g) — spot urine albumin-to-creatinine ratio

Related Scores in Practice

In clinical practice, this assessment is frequently evaluated alongside other validated measures. Depending on the patient's presentation and specific diagnostic requirements, you may also need to utilize the Egfr Calc, CKD Stage (KDIGO) or the UACR to formulate a comprehensive care plan.

Last Comprehensive Review: 2026

Related Nephrology Tools

Uric Acid & FEUA

Urinary Anion Gap

Winter's Formula

Urea Reduction Ratio

Electrolyte & Free Water

Sodium Correction

Nephrology Calculators Internal Medicine Calculators Emergency Medicine Calculators

Have feedback about this calculator?Let us know.