OpiCalc Logo

OpiCalc

989 Clinical Tools

Logo
OpiCalc
AMD Severity ScaleAstigmatism AssistantBarrett / SRK-T SimDiabetic Retinopathy RiskGlaucoma ProgressionGlaucoma Risk (OHTS)Graves CASHFA MD to VFI ConverterIOP Correction (CCT)LogMAR <-> SnellenMRD AssessmentROP Risk (G-ROP)SPEED Score (Dry Eye)SUN Uveitis GradingVertex Distance
OpiCalc Logo

OpiCalc

Open-access clinical infrastructure. Built to the standard every clinician deserves — fast, private, and free.

Zero data stored
Always free
Our mission & transparency

Get in Touch

Tool request, clinical feedback, or partnership inquiry — we read everything.

WhatsApp feedback
Email us
Partnership inquiry

© 2026 OpiCalc • Calculated Care

ProtocolsAboutPrivacyTerms

Graves CAS

Clinical Activity Score

0/7
Inactive Phase
Guidelines & Evidence

Clinical Details

Section 1

When to Use

Assessment Goal

The Clinical Activity Score (CAS) is used to determine if thyroid-associated ophthalmopathy (TAO) is in the active, inflammatory phase where immunosuppression (e.g. steroids, Teprotumumab) is most effective.
Section 2

Formula & Logic

Initial 7 Parameters (1 pt each)

Spontaneous retrobulbar pain
Pain on attempted up or down gaze
Redness of eyelids
Redness of conjunctiva (diffuse)
Swelling of eyelids
Chemosis (swelling of conjunctiva)
Swelling of the caruncle or plica

Interpretation

Active disease is defined as a CAS ≥ 3/7 at the first visit.

Last Comprehensive Review: 2026

Related Ophthalmology Tools

AMD Severity Scale
Astigmatism Assistant
Barrett / SRK-T Sim
Diabetic Retinopathy Risk
Glaucoma Progression
Glaucoma Risk
HFA MD to VFI Converter
IOP Correction
LogMAR <-> Snellen
MRD Assessment
Have feedback about this calculator?Let us know.