Metastatic RCC — First-line Systemic Therapy6 Prognostic Factors (1 pt each)Time from initial diagnosis to systemic therapy < 1 yearKarnofsky Performance Status (KPS) < 80%Hemoglobin below lower limit of normal (LLN)Corrected serum calcium above upper limit of normal (ULN)Neutrophil count above upper limit of normal (ULN)Platelet count above upper limit of normal (ULN)All values assessed at initiation of first-line systemic therapy. Calcium corrected for albumin.Reset
