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Clinical Notice:OpiCalc is not a substitute for professional clinical judgment. Always verify dosages and guidelines.

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Recent Journal Updates

Pan American Health OrgJun 18, 2026
PAHO Executive Committee concludes 178th session with key decisions to strengthen health across the Americas

Clinical Context

We think this might be relevant to the clinical guidance for VUR Grading (International Reflux Study Committee).

BJOGJun 17, 2026
Anatomical–Motor Level Discrepancy in Prenatal Diagnosis of Open Spinal Dysraphism: A 12‐Year Retrospective Observational Study

Clinical Context

We think this might be relevant to the clinical guidance for VUR Grading (International Reflux Study Committee).

WHO NewsJun 15, 2026
Open letter to leaders of G7, G20, BRICS and all nations on finalizing the WHO Pandemic Agreement’s Pathogen Access and Benefit Sharing annex

Clinical Context

We think this might be relevant to the clinical guidance for VUR Grading (International Reflux Study Committee).

VUR Grading

VUR Classification — International Reflux Study Committee

VCUG Grading Criteria

Select the grade observed on voiding cystourethrogram (VCUG):

Select a VUR Grade

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

When to Perform VCUG and Grade VUR

First febrile urinary tract infection (UTI) in children under 2 years (especially boys)
Recurrent febrile UTIs in older children
Prenatal hydronephrosis with persistent postnatal dilation
Abnormal bladder on ultrasound (thickened wall, diverticula, or ureterocele)
Family history of VUR or renal scarring in siblings
Neurogenic bladder or voiding dysfunction with recurrent infections
Follow-up after endoscopic injection or ureteral reimplantation to assess resolution
Pre-transplant evaluation in select cases

Clinical Importance

Vesicoureteral reflux (VUR) is the retrograde flow of urine from the bladder into the ureter and/or kidney. It is a major risk factor for pyelonephritis and renal scarring in children. The International Reflux Study Committee grading system, based on voiding cystourethrogram (VCUG), remains the gold standard for classifying severity and guiding management decisions between conservative observation, antibiotic prophylaxis, endoscopic therapy, and surgical reimplantation.

Last Comprehensive Review: 2026

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