ABCD2 Score

Aspirin 300mg should be started immediately after TIA (as soon as haemorrhage excluded by CT). Do not delay for MRI in high-risk patients. Dual antiplatelet therapy (aspirin + clopidogrel) for 21 days further reduces stroke risk (POINT/CHANCE trials).

The ABCD2 score was created by combining two independently derived scores: the California score (Johnston et al. 2000) and the Oxford ABCD score (Rothwell et al. 2005). The combined score (published in Lancet, 2007) outperformed either component score. It has since been incorporated into NICE CG68 (2008) and AHA/ASA TIA management guidelines.