Verified
Last Review: 2026
| Transudates | CHF (86%), Cirrhosis (7%), Nephrotic Syndrome, Peritoneal Dialysis. |
| Exudates | Malignancy (41%), Infection/Pneumonia (25%), TB (9%), PE, Uremia. |
Porcel JM et al. • ERJ Open Research. 2026;Large-scale study (n=7280) proving that a PF-only combination of protein, LDH, and cholesterol matches Light's accuracy while improving specificity for transudates.
View SourceYang DN et al. • Scientific Reports. 2025;Analyzed the positive correlation between CEA and LDH/Protein levels; found that LDH ratio >0.6 predicts false-negative CEA in MPE.
View SourceLight RW et al. • Annals of Internal Medicine. 1972;The seminal paper that established the protein and LDH ratios as the clinical standard for the last 50+ years.
View SourceLast Comprehensive Review: 2026
Clinical Context
We think this might be relevant to the clinical guidance for Light's Criteria.
Clinical Context
We think this might be relevant to the clinical guidance for Light's Criteria.
Clinical Context
We think this has broad domain relevance to Light's Criteria.
