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TTKG

Transtubular Potassium Gradient (TTKG): Assesses aldosterone activity and renal handling of potassium in hyper/hypokalemia.

K (mEq/L)

Osm (mOsm/kg)

K (mEq/L)

Osm (mOsm/kg)

Na (mEq/L)

Guidelines & Evidence

Verified

Last Review: 2026-07-17

When to Use

How it Works

Clinical Pearls

Next Steps

The Evidence

Origins & History

Last Comprehensive Review: 2026-07-17

Recent Journal Updates

WHO NewsJul 2, 2026
WHO adds first diagnostic test for Ebola Bundibugyo virus to its Emergency Use Listing

Clinical Context

We think this has broad domain relevance to TTKG.

BJOGJun 25, 2026
Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review

Clinical Context

We think this has broad domain relevance to TTKG.