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HAM-D 17 (Hamilton Depression)

Hamilton Depression Rating Scale (HAM-D 17)

Clinician-administered assessment for depression severity. Complete all 17 items based on clinical observation and patient interview.

1

Depressed Mood

Sadness, hopelessness, helplessness, worthlessness

2

Feelings of Guilt

Self-reproach, ideas of guilt

3

Suicide

Thoughts, gestures, or attempts

4

Insomnia (Early)

Difficulty falling asleep

5

Insomnia (Middle)

Waking during the night

6

Insomnia (Late)

Waking in early hours

7

Work and Activities

Loss of interest, decreased productivity

8

Retardation

Slowness of thought and speech

9

Agitation

Restlessness, pacing, hand-wringing

10

Anxiety (Psychic)

Tension, irritability, worry

11

Anxiety (Somatic)

Physical correlates of anxiety (GI, CV, etc.)

12

Somatic Symptoms (GI)

Loss of appetite, constipation

13

Somatic Symptoms (General)

Heaviness in limbs, backache, headache

14

Genital Symptoms

Loss of libido, menstrual disturbances

15

Hypochondriasis

Preoccupation with physical health

16

Loss of Weight

Measured or reported by patient

17

Insight

Understanding of being depressed

© OpiCalc Clinical Intelligence

Hamilton M. (1960)

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

Application Guide

Quantifying the severity of depressive symptoms in patients with a confirmed diagnosis of Major Depressive Disorder (MDD).

Gold standard for clinical trials and monitoring pharmaceutical treatment response.

Assessing specific somatic vs. psychological symptom clusters (e.g., insomnia, weight loss, agitation).

Evaluating suicidality risk as part of a comprehensive psychiatric review.

Clinical Environment

The HAM-D 17 is a clinician-administered scale. Unlike the PHQ-9, it requires a trained professional to interview the patient and observe non-verbal cues (e.g., psychomotor retardation).

Last Comprehensive Review: 2026

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