QTc Safety: Use Fridericia (QTcF) or Bazett (QTcB) corrected values. High risk if QTc > 470-500 ms or multiple risk factors present.
Female sex
Age ≥ 65 years
Prior history of structural heart disease
Known Hypokalemia (<3.5 mEq/L)
Baseline Bradycardia (<60 bpm)
Use of ≥1 other QTc prolonging agent
Family history of sudden cardiac death
