ACE-III (Cognitive Examination)AIMS (Tardive Dyskinesia)ASRM (Altman Mania Scale)ASRS-v1.1 (Adult ADHD Screen)ASSIST (WHO Substance Screen)AUDIT (Alcohol Use Disorders)AUDIT-C (Alcohol Screen)Alzheimer's Disease Assessment Scale — Cognitive (ADAS-Cog)Anxiety Sensitivity Index-3 (ASI-3)BARS (Akathisia)BDI-II (Beck Depression)BPRS (Brief Psychiatric Rating)BSDS (Bipolar Spectrum Screen)Beck Anxiety Inventory (BAI)Behavior Rating Inventory of Executive Function — Adult (BRIEF-A)Binge Eating Scale (BES)Borderline Personality Disorder Severity Index (BPDSi)Brief Positive and Negative Syndrome Scale (PANSS-6)C-SSRS (Suicide Severity)CAGE Questionnaire CAPS-5 (PTSD Clinical Interview)CDR (Dementia Staging)CDSS (Schizophrenia Depression)CIWA-Ar (Alcohol Withdrawal)COWS (Opioid Withdrawal)Cannabis Use Disorder Identification Test — Revised (CUDIT-R)Clinical Global Impression (CGI-S & CGI-I)Clinical Global Impression — Bipolar (CGI-BP)Clinical Global Impression — Schizophrenia (CGI-SCH)Clinical Impairment Assessment (CIA 3.0)Clinical Institute Withdrawal Assessment for Benzodiazepines (CIWA-B)Clozapine Safety (REMS)Conners' Adult ADHD Rating Scales (CAARS)DAST-10 (Drug Abuse Screen)DES-II (Dissociation Scale)DISCERN (Antidepressant Decision Aid)EDE-Q (Eating Disorder Severity)EPDS (Postnatal Depression)Eating Attitudes Test (EAT-26)Epworth Sleepiness Scale FAST (Alzheimer's Staging)Fagerstrom (Nicotine Dependence)Functional Activities Questionnaire (FAQ)GAD-2 (Anxiety Screen)GAD-7 (Anxiety Severity)GAF (Global Functioning)HAM-D 17 (Hamilton Depression)HCL-32 (Hypomania Checklist)Hamilton Anxiety Rating Scale (HAM-A)IES-R (Trauma Impact)ISI (Insomnia Severity)International Restless Legs Scale (IRLS)International Trauma Questionnaire (ITQ)Inventory of Depressive Symptomatology (IDS-C30)LSAS (Social Anxiety)Lithium Toxicity Level Interpreter MADRS (Depression Rating)MARSIPAN (Medical Risk in AN)MDQ (Bipolar Screen)MSI-BPD (Borderline PD Screen)Manchester Self Harm Mania Symptom Scale (MSS)Metabolic Syndrome (Psych)MoCA (Cognitive Assessment)Neuropsychiatric Inventory (NPI)OCI-R (OCD Screen)Opioid Risk Tool (ORT)Overall Anxiety Severity and Impairment Scale (OASIS)PANSS (Schizophrenia Severity)PATHOS Self-Harm Screen PCL-5 (PTSD Checklist DSM-5)PHQ Panic Module PHQ-2 (Depression Screen)PHQ-9 (Depression Severity)PSP (Personal/Social Performance)PSQI (Pittsburgh Sleep Quality)Panic Disorder Severity Scale (PDSS)Patient Health Questionnaire for Adolescents (PHQ-A)Primary Care PTSD Screen for DSM-5 (PC-PTSD-5)QTc Prolongation (Psychiatry)Quick Inventory of Depressive Symptomatology (QIDS-SR-16)RLS Diagnostic Criteria (IRLSSG)Reasons for Living Inventory (RFL)Rowland Universal Dementia Assessment Scale (RUDAS)SAD Persons SAFE-T Protocol SBQ-R (Suicidal Behaviors)SCOFF (Eating Disorder Screen)SPIN (Social Phobia)Screen for Child Anxiety Related Disorders (SCARED)Simpson-Angus Scale (EPS)Y-BOCS (OCD Severity)YMRS (Mania Severity)

MADRS (Depression Rating)

MADRS: Montgomery-Åsberg Depression Rating Scale. A sensitive clinician-rated tool to measure depression severity.

Item 1

Apparent Sadness

Representing despondency, gloom and despair, (more than just ordinary transient low spirits) reflected in speech, facial expression, and posture.

Item 2

Reported Sadness

Representing reports of depressed mood, whether it is reflected in appearance or not. Includes low spirits, despondency or the feeling of being beyond help and without hope.

Item 3

Inner Tension

Representing feelings of ill-defined discomfort, edginess, inner turmoil, mental tension mounting to panic, dread and anguish.

Item 4

Reduced Sleep

Representing a reduction in the duration or depth of sleep compared to the subject's own normal pattern when well.

Item 5

Reduced Appetite

Representing a feeling of loss of appetite compared with when well.

Item 6

Concentration Difficulties

Representing difficulties in collecting one's thoughts mounting to incapacitating lack of concentration.

Item 7

Lassitude

Representing a difficulty in getting started or slowness in initiating and performing everyday activities.

Item 8

Inability to Feel

Representing the subjective experience of reduced interest in the surroundings, or activities that normally give pleasure.

Item 9

Pessimistic Thoughts

Representing ideas of guilt, inferiority, self-reproach, sinfulness, remorse and ruin.

Item 10

Suicidal Thoughts

Representing the feeling that life is not worth living, that a natural death would be welcome, suicidal thoughts, and preparations for suicide.

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

When to Use

Clinician-rated assessment of depression severity in diagnosed MDD

Primary outcome measure in antidepressant clinical trials (drug registration studies)

Treatment response monitoring at baseline, week 1–2, and week 4–6 of therapy

Preferred over HAM-D when sensitivity to antidepressant-induced change is required

Last Comprehensive Review: 2026

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