NPI: Neuropsychiatric Inventory. Informant-rated assessment of BPSD. Toggle each domain "Present" to rate its Frequency, Severity, and Caregiver Distress.
BPSD Screening (0/12)
Guidelines & Evidence
Clinical Details
Section 1
When to Use
When to Use
Assessment of Behavioral and Psychological Symptoms of Dementia (BPSD)
Monitoring treatment response for neuropsychiatric symptoms in AD, FTD, or Vascular Dementia
Evaluating caregiver distress related to specific patient behaviors
Standardized measurement in clinical trials targeting behavioral outcomes in neurodegeneration
Section 2
Formula & Logic
Scoring Logic
The NPI evaluates 12 behavioral domains. For each domain present, the clinician rates: (1) Frequency (1-4), (2) Severity (1-3), and (3) Caregiver Distress (0-5). The Domain Score is Frequency × Severity (0-12).
Behavioral Domains
Delusions, Hallucinations, Agitation/Aggression
Depression/Dysphoria, Anxiety, Elation/Euphoria
Apathy/Indifference, Disinhibition
Irritability/Lability, Aberrant Motor Behavior
Nighttime Behavior, Appetite/Eating Changes
Section 3
Evidence Appraisal
Validation
The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia.
Cummings JL et al. • Neurology.. 1994;44(12):2308-14. Original validation showing high reliability and sensitivity to clinical interventions.
The Neuropsychiatric Inventory: assessing psychopathology in dementia patients.
Cummings JL. • Int Psychogeriatr.. 1996;Highlighted the NPI as a critical regulatory and clinical standard for BPSD evaluation.
