MSS: Mania Symptom Scale. Clinician-rated assessment for mixed and psychotic mania. Rate symptoms from 0 (Absent) to 4 (Extreme).
Clinical Manic Profile (0/14)
Increased Motor Activity
Activation
Pressured Speech
Activation
Flight of Ideas
Activation
Increased Energy
Activation
Decreased Need for Sleep
Activation
Euphoria / Elation
Elation
Grandiosity
Elation
Hallucinations
Psychosis
Delusions
Psychosis
Paranoia
Psychosis
Irritability
Dysphoria
Aggressive Behavior
Dysphoria
Lability of Mood
Dysphoria
Depressive Symptoms
Dysphoria
Guidelines & Evidence
Clinical Details
Section 1
When to Use
When to Use
Assessment of mania severity in patients with Bipolar I Disorder
Screening for mixed features (concomitant depressive symptoms) in manic episodes
Evaluating the presence and impact of psychotic symptoms in mania
Monitoring treatment response across the full spectrum of manic phenomenology
Section 2
Formula & Logic
Scoring Logic
The MSS consists of 14 clinician-rated items. It uniquely highlights the three core factors of mania: Elation/Activation, Psychosis/Hyper-activity, and Irritability/Dysphoria.
Interpreting Mixed Features
High scores on the Irritability/Dysphoria items in the presence of manic activation suggest a mixed-episode presentation with higher risk for suicide and treatment resistance.
Section 3
Evidence Appraisal
Validation
A mania symptom scale validated for mixed-state and psychotic mania.
Cassidy F et al. • Am J Psychiatry.. 1998;155(15):1741-7. Found the MSS to be superior to the YMRS for capturing mixed-state phenomenology.
