Acute Chronic HBV ALT 70 Aminoglycoside Extended Interval Antibiotic Duration Guide Antibiotic PKPD Optimisation APACHE II Sepsis Context ATS IDSA CAP Severity Bacteremia Risk Shapiro Bacterial Meningitis Score C difficile Severity Recurrence CAUTI Criteria CD4 OI Risk Centor Criteria CISNE Score Congenital Syphilis Risk CPIS CSF Interpretation CURB-65 De Escalation Eligibility Dengue NS1 IgM Dengue Severity WHO Diabetic Foot Infection DRIP Score Duke Criteria Embolic Risk IE Eron Classification ESC 2023 IE Risk Fever PAIN GCCT Treatment GCS CNS Infection HBV Post Exposure Prophylaxis HBV Reactivation Risk HBV Treatment Eligibility HCV DAA Eligibility HCV Fibrosis APRI HCV Fibrosis FIB4 HIV Drug Interaction Checker HIV Pre Test Probability IGRA Interpretation Kocher Criteria Legionella Predictor Lemierre Risk Flags Leptospirosis Faine Score Lights Criteria LRINEC Score LTBI Treatment Eligibility Malaria Pre Test Probability Malaria Severity WHO MASCC Score McIsaac Score MDR TB Suspicion Measles Criteria Modified Duke Criteria MSIS Criteria Needlestick Exposure Risk nPEP Eligibility Occupational HIV PEP OI Prophylaxis Restart ORENUC Classification PAGE B Score Parapneumonic Effusion Complexity Parapneumonic PH Management PCP Prophylaxis PENS Score Peritonsillar Abscess Score PID Severity Classification Pitt Bacteremia Score PrEP Candidacy Procalcitonin Stop Rule PSI PORT Score Renal Dose Adjustment Returning Traveller Fever Rhinosinusitis EPOS SBP Criteria SCORTEN Sepsis 3 Criteria Septic Shock Criteria SMART COP STI Syndromic Tool Syphilis Interpretation TB IRIS Risk TB Regimen Calculator TB Risk Score TST Interpretation UTI Risk VACS Index Vancomycin AUC Dosing VZIG Eligibility

Recent Journal Updates

WHO NewsJun 5, 2026

Africa CDC and WHO launch joint continental Ebola response plan

Clinical Context

We think this has broad domain relevance to LRINEC Score for Necrotizing Fasciitis.

JAMAJun 2, 2026

Virtual Neurology Visits Comparable With In-Person for Initial Evaluations

Clinical Context

We think this has broad domain relevance to LRINEC Score for Necrotizing Fasciitis.

WHO NewsMay 31, 2026

Joint statement by the Government of the Democratic Republic of the Congo and WHO concerning the outbreak of Ebola disease caused by the Bundibugyo virus

Clinical Context

We think this has broad domain relevance to LRINEC Score for Necrotizing Fasciitis.

LRINEC Score

Triage Support • Necrotizing Fasciitis (NSTI) Risk Triage

LRINEC Score Calculator for Necrotizing Fasciitis

Standardized risk assessment tool to estimate the probability of Necrotizing Soft Tissue Infections (NSTI) and triage for emergency surgical debridement.

Laboratory Parameters

CRP (mg/L)

WBC (x10³/mm³)

Hemoglobin (g/dL)

Sodium (mEq/L OR mmol/L)

Creatinine (mg/dL)

Glucose (mg/dL)

Risk Profile

Low Risk

Score: 0 / 13

Low statistical risk, however 37% of NF cases score < 6. Maintain high clinical suspicion.

Clinical Caveat: The LRINEC score has low sensitivity and should not be used to definitively rule out necrotizing fasciitis. Early emergency surgical debridement remains the cornerstone of necrotizing soft tissue infection (NSTI) management regardless of the score. Serial calculation may help monitor sepsis resolution post-debridement.

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

Primary Clinical Usage

Differential diagnosis of severe soft tissue infections (cellulitis vs. necrotizing fasciitis).

Triage of patients with "pain out of proportion" to physical exam findings.

Initial risk stratification in emergency departments and primary care units.

Monitoring the clinical course post-surgical debridement (tracking score decrease).

Defining Necrotizing Fasciitis

NF is a life-threatening emergency characterized by rapid necrosis of subcutaneous tissue and deep fascia. Lethality ranges from 20-30% and approaches 100% without rapid intervention.

Related Scores in Practice

In clinical practice, this assessment is frequently evaluated alongside other validated measures. Depending on the patient's presentation and specific diagnostic requirements, you may also need to utilize the Sepsis 3 Criteria, qSOFA, SIRS Criteria, Eron Classification or the Diabetic Foot Infection to formulate a comprehensive care plan.

Last Comprehensive Review: 2026

Related Infectious Disease Tools

Diabetic Foot Infection

Infectious Disease Calculators Internal Medicine Calculators Emergency Medicine Calculators

Have feedback about this calculator?Let us know.

Recent Journal Updates

WHO NewsJun 5, 2026

Africa CDC and WHO launch joint continental Ebola response plan

Clinical Context

We think this has broad domain relevance to LRINEC Score for Necrotizing Fasciitis.

JAMAJun 2, 2026

Virtual Neurology Visits Comparable With In-Person for Initial Evaluations

Clinical Context

We think this has broad domain relevance to LRINEC Score for Necrotizing Fasciitis.

WHO NewsMay 31, 2026

Joint statement by the Government of the Democratic Republic of the Congo and WHO concerning the outbreak of Ebola disease caused by the Bundibugyo virus

Clinical Context

We think this has broad domain relevance to LRINEC Score for Necrotizing Fasciitis.

LRINEC Score

Triage Support • Necrotizing Fasciitis (NSTI) Risk Triage

LRINEC Score Calculator for Necrotizing Fasciitis

Standardized risk assessment tool to estimate the probability of Necrotizing Soft Tissue Infections (NSTI) and triage for emergency surgical debridement.

Laboratory Parameters

CRP (mg/L)

WBC (x10³/mm³)

Hemoglobin (g/dL)

Sodium (mEq/L OR mmol/L)

Creatinine (mg/dL)

Glucose (mg/dL)

Risk Profile

Low Risk

Score: 0 / 13

Low statistical risk, however 37% of NF cases score < 6. Maintain high clinical suspicion.

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

Primary Clinical Usage

Differential diagnosis of severe soft tissue infections (cellulitis vs. necrotizing fasciitis).

Triage of patients with "pain out of proportion" to physical exam findings.

Initial risk stratification in emergency departments and primary care units.

Monitoring the clinical course post-surgical debridement (tracking score decrease).

Defining Necrotizing Fasciitis

NF is a life-threatening emergency characterized by rapid necrosis of subcutaneous tissue and deep fascia. Lethality ranges from 20-30% and approaches 100% without rapid intervention.

Related Scores in Practice

Last Comprehensive Review: 2026

Related Infectious Disease Tools

Diabetic Foot Infection

Infectious Disease Calculators Internal Medicine Calculators Emergency Medicine Calculators

Have feedback about this calculator?Let us know.