MSIS Criteria: Major and minor prosthetic joint infection diagnostic features.
Assessment Tier
Low
Score 0
Selected features provide limited support for PJI.
Verified
Last Review: 2026-07-17
Use during early bedside triage when infection severity or treatment escalation is uncertain.
Support clinician judgement with a structured review of the highest-yield risk factors.
Standardise communication between admitting, ID, ICU, and pharmacy teams.
Sinus tract to prosthesis (+3)
Two positive cultures with same organism (+3)
Elevated synovial WBC/PMN (+2)
Purulence around prosthesis (+2)
Positive histology / single culture (+1)
Interpret the result together with source control, microbiology, host factors, and trajectory.
Escalate imaging, cultures, or specialist review when the tool lands in a high-risk tier.
Reassess dynamically if the patient deteriorates or new microbiology becomes available.
This tool supports structured infectious-disease decision making but does not replace clinician judgement or local guideline pathways.
This OpiCalc infectious-disease entry reflects commonly used guideline criteria and bedside risk features used in contemporary clinical practice.
Last Comprehensive Review: 2026-07-17