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AST-to-Platelet Ratio Index (APRI Score)Acute Liver Failure Study Group Index (ALFSG Index)Age, Bilirubin, INR and Creatinine Score (ABIC Score)Albumin-Bilirubin Grade (ALBI Score)BMI, AST/ALT Ratio, and Diabetes Score (BARD Score)CLIF-C ACLF Score for Acute-on-Chronic Liver Failure (CLIF-C ACLF)CLIF-C AD Score for Acute Decompensation of Cirrhosis (CLIF-C AD)CLIF-SOFA Score for Organ Failure Assessment (CLIF-SOFA)Cancer of the Liver Italian Program Score (CLIP Score)Child-Pugh Classification for Cirrhosis (Child-Pugh)Chinese University Prognostic Index (CUPI Score)Fibrosis-4 Index (FIB-4 Index)Lille Model for Alcoholic Hepatitis (Lille Model)Maddrey Discriminant Function (Maddrey DF)Model for End-Stage Liver Disease (MELD Score)NAFLD Fibrosis Score (NFS)Simplified Autoimmune Hepatitis Score (Simplified AIH)
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Cancer of the Liver Italian Program Score (CLIP Score)

Cancer of the Liver Italian Program Score (CLIP Score)

HCC Prognosis & Staging System

Integrated Clinical & Morphologic Staging

CLIP Staging Engine

Select tumor and hepatic parameters to determine the CLIP prognosis.

Guidelines & Evidence

Verified

Last Review: 2026

Clinical Significance

Integrating Liver and Tumor

In HCC, the prognosis is determined by two factors: the burden of the cancer and the underlying severity of the cirrhosis. CLIP was one of the first scores to successfully integrate both.

Survival in Advanced Disease

While systems like BCLC are used for treatment selection, the CLIP score is particularly granular for predicting survival in patients with advanced HCC who are not surgical candidates.

Objective Staging

Using objective markers like AFP levels and portal vein thrombosis (PVT) makes CLIP highly reproducible across different clinical centers.

Last Comprehensive Review: 2026

Related Hepatology Tools

Child-Pugh Classification for Cirrhosis
NAFLD Fibrosis Score
Chinese University Prognostic Index
Fibrosis-4 Index
Cancer of the Liver Italian Program Score
Albumin-Bilirubin Grade
Maddrey Discriminant Function
Model for End-Stage Liver Disease
AST-to-Platelet Ratio Index
Age, Bilirubin, INR and Creatinine Score
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