Note: Assessment of clinical volume status (Euvolaemic vs Hypovolaemic) is essential to distinguish SIADH from CSW (Cerebral Salt Wasting).
Verified
Last Review: 2026
| Parameter | DI (Diabetes Insipidus) | SIADH |
|---|---|---|
| Serum Sodium | High (> 145) | Low (< 135) |
| Serum Osmolality | High (> 295) | Low (< 275) |
| Urine Osmolality | Inappropriately Low (< 300) | Inappropriately High (> 100) |
| Urine Sodium | Variable | High (> 40 mEq/L) |
| Volume Status | Hypovolaemic / Euvolaemic | Euvolaemic |
Fenske W et al. • J Clin Endocrinol Metab. 2012;The standard reference for differential diagnosis of hyponatraemia syndromes.
Last Comprehensive Review: 2026
Clinical Context
We think this might be relevant to the clinical guidance for DI vs SIADH Differentiator.
Clinical Context
We think this might be relevant to the clinical guidance for DI vs SIADH Differentiator.
Clinical Context
We think this might be relevant to the clinical guidance for DI vs SIADH Differentiator.
