CRITICAL SAFETY: Do not exceed a correction rate of 8-10 mEq/L in any 24-hour period (6 mEq/L in high-risk patients) to avoid ODS (Osmotic Demyelination Syndrome).
Verified
Last Review: 2026
| Fluid | Sodium Concentration |
|---|---|
| 3.0% Saline | 513 |
| 0.9% Saline | 154 |
| Lactated Ringer's | 130 |
Adrogué HJ et al. • N Engl J Med. 2000;The foundational study describing the fluid correction formula and ODS risks.
Last Comprehensive Review: 2026
Clinical Context
We think this might be relevant to the clinical guidance for Hyponatraemia Correction Rate Calculator.
Clinical Context
We think this might be relevant to the clinical guidance for Hyponatraemia Correction Rate Calculator.
Clinical Context
We think this might be relevant to the clinical guidance for Hyponatraemia Correction Rate Calculator.
