CARPREG II Cardiac Risk

CARPREG II Risk Score

Maternal Cardiac Risk Index

Calculated Cardiac Risk Score

0

Prob. Primary Cardiac Event

Primary cardiac events include: heart failure, sustained arrhythmia, stroke, myocardial infarction, or cardiac death.

Guidelines & Evidence

Verified

Last Review: 2026-07-17

When to Use

Primary Clinical Uses

Predicting the risk of primary maternal cardiac complications during pregnancy

Risk stratification for women with pre-existing congenital or acquired heart disease, or arrhythmias

Pre-pregnancy counseling to establish realistic expectations regarding maternal morbidity

When NOT to Use

The CARPREG II score is designed to predict MATERNAL cardiac outcomes, not fetal or neonatal outcomes. Furthermore, it does not factor in obstetric risk factors (e.g., maternal age, extreme obesity, or preeclampsia risk) which can independently exacerbate cardiac reserve.

How it Works

Scoring Variables

Prior cardiac event or arrhythmia	3 points
Baseline NYHA class III-IV or cyanosis	3 points
Mechanical heart valve	3 points
Systemic ventricular dysfunction (LVEF <55%)	2 points
High-risk left-sided valve disease / LVOT obstruction	2 points
Pulmonary hypertension (RVSP >49 mmHg)	2 points
Coronary artery disease	2 points
High-risk aortopathy	2 points
No prior cardiac intervention	1 point
Late pregnancy assessment (>20 weeks)	1 point

Risk of Primary Cardiac Event

0–1 Point	5% Risk
2 Points	10% Risk
3 Points	15% Risk
4 Points	22% Risk
≥ 5 Points	41% Risk

Last Comprehensive Review: 2026-07-17

In Recent Clinical News

Scanning Medical Journals

No new significant updates or guidelines matching this topic were found today. We will check again soon.

CARPREG II Cardiac Risk

CARPREG II Risk Score

0

When to Use

Primary Clinical Uses

When NOT to Use

How it Works

Scoring Variables

Risk of Primary Cardiac Event

Clinical Pearls

Key Strengths

Known Limitations

Next Steps

High Risk (Score ≥ 4)

Complementary Guidelines

The Evidence

Primary Derivation Reference

Pregnancy Outcomes in Women With Heart Disease: The CARPREG II Study.

Origins & History

The CARPREG Registry

In Recent Clinical News

CARPREG II Cardiac Risk

CARPREG II Risk Score

0

When to Use

Primary Clinical Uses

When NOT to Use

How it Works

Scoring Variables

Risk of Primary Cardiac Event

Clinical Pearls

Key Strengths

Known Limitations

Next Steps

High Risk (Score ≥ 4)

Complementary Guidelines

The Evidence

Primary Derivation Reference

Pregnancy Outcomes in Women With Heart Disease: The CARPREG II Study.

Origins & History

The CARPREG Registry

In Recent Clinical News