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PAS Hemorrhage Risk

PAS Spectrum Risk

Placenta Accreta / Increta / Percreta Assessment

High-Yield Ultrasound Markers

  • Prior Cesarean Section (Weighted Rank 1)
  • Placenta Previa (Co-existing)
  • Multiple Placental Lacunae
  • Loss of retroplacental clear zone
  • Abnormal uterine-bladder interface
  • Exophytic mass (Extra-uterine extension)

Massive Transfusion (MTP)

WHO/FIGO Aligned Protocol: 1:1:1 Ratio (RBC : FFP : Platelets).

Hb Target> 7g/dL
Plt Target> 50k
Fib Target> 200mg/dL
Critical Bleeding RateExceeding 150mL / Minute
Guidelines & Evidence

Verified

Last Review: 2026-07-17

When to Use

Primary Clinical Uses

Classifying the profound morbidity risk in patients presenting with placenta previa and prior cesarean sections.
Directing surgical planning (e.g., scheduled cesarean hysterectomy, massive transfusion protocols).
Pre-operative counseling regarding the extreme risk of catastrophic pelvic hemorrhage.

What is PAS?

Placenta Accreta Spectrum (PAS) involves abnormal trophoblast invasion into the myometrium. It is categorized into Accreta (attaches directly to myometrium), Increta (invades into myometrium), and Percreta (penetrates through serosa/bladder).

How it Works

Risk Amplification (Silver et al.)

Calculated Risk with Placenta Previa:Exponential Increase
0 Prior Cesareans3% risk of Accreta
1 Prior Cesarean11% risk
2 Prior Cesareans40% risk
3 Prior Cesareans61% risk
4+ Prior Cesareans67% risk

Key Ultrasound Markers

Multiple irregular placental lacunae ("Swiss cheese" appearance)
Loss of the normal retroplacental clear space
Myometrial thickness < 1 mm
Bridging vessels spanning from placenta into bladder wall (Percreta)

Clinical Pearls

Absolute Contraindications

DO NOT attempt manual removal of the placenta if PAS is aggressively suspected or confirmed intraoperatively. Forcing a cleavage plane will trigger instant, massive, and virtually uncontrollable pelvic hemorrhage.
If diagnosed unexpectedly upon opening the abdomen during a routine C-section, do not disturb the placenta. Close the hysterotomy, pack the abdomen if needed, and call immediately for Gynecologic Oncology or a highly experienced surgical rescue team.

Next Steps

Surgical Pathway (Confirmed Increta/Percreta)

01
Schedule controlled delivery at 34 0/7 to 35 6/7 weeks.
02
Assemble multidisciplinary team: MFM, Gyn Oncology, Urologist (for ureteral stents), Trauma/Transfusion Medicine.
03
Perform classical (vertical) hysterotomy vastly superior to the placental edge to deliver the infant without cutting through the placenta.
04
Leave placenta strictly *in situ* undisturbed.
05
Proceed directly to total hysterectomy with the placenta still inside the uterus.

The Evidence

Landmark References

Maternal morbidity associated with multiple repeat cesarean deliveries.

Silver RM et al. • Obstet Gynecol.. 2006;The massive definitive database study establishing the exact percentages mapping cesarean section count directly to Placenta Accreta risk in the presence of previa.

Placenta Accreta Spectrum.

ACOG Obstetric Care Consensus No. 7. • Obstet Gynecol.. 2018;Provides the current U.S. national standards for screening, ultrasound diagnosis, blood-banking preparation, and intentional non-removal algorithms.

Origins & History

A Man-Made Epidemic

Placenta Accreta was exceptionally rare before the 1980s. The colossal rise in global cesarean section delivery rates created a man-made pathological phenomenon where fertilized eggs preferentially implant over scarred, defective anterior lower uterine segment tissue.

Last Comprehensive Review: 2026-07-17

In Recent Clinical News

Scanning Medical Journals

No new significant updates or guidelines matching this topic were found today. We will check again soon.