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Clinical Notice:OpiCalc is not a substitute for professional clinical judgment. Always verify dosages and guidelines.

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IVF Due Date & AMH

IVF Due Date Calculator

Based on Embryo Age at Transfer

AMH Ranges (Fertility)

Polycystic (PCOM)

> 3.3 ng/mL

Optimal / Normal

1.5–3.3 ng/mL

Low Reserve

0.7–1.5 ng/mL

Very Low Reserve

< 0.7 ng/mL

Guidelines & Evidence

Verified

Last Review: 2026-07-17

When to Use

Primary Clinical Uses

Accurately determining the Estimated Date of Delivery (EDD) and Estimated Gestational Age (EGA) for pregnancies conceived via In Vitro Fertilization.
Bypassing the standard Last Menstrual Period (LMP) method entirely due to ovulation induction suppression.
Interpreting Anti-Müllerian Hormone (AMH) levels for ovarian reserve testing.

The Dating Mandate

In an IVF pregnancy, the exact date of fertilization is a known scientific fact. Under no circumstances should early ultrasound/crown-rump length or LMP override the calculated IVF date. The IVF date is neurologically absolute.

How it Works

Formula Rules

Standard Human Gestational Period = 280 days (from LMP) or 266 days (from conception).
For a Day 3 Embryo (Cleavage Stage): EDD = Transfer Date + 266 Days - 3 Days
For a Day 5 Embryo (Blastocyst): EDD = Transfer Date + 266 Days - 5 Days

AMH Interpretation

> 3.3 ng/mLHigh / PCOM morphology (risk of Ovarian Hyperstimulation Syndrome)
1.5 – 3.3 ng/mLNormal / Optimal fertility reserve
0.7 – 1.5 ng/mLLow reserve (accelerated diminished ovarian reserve)
< 0.7 ng/mLVery low reserve (poor responder to egg retrieval)

Clinical Pearls

Key Misconceptions

A very low AMH (<0.7) means the patient will have immense difficulty retrieving multiple eggs during IVF. It DOES NOT mean the patient cannot spontaneously get pregnant globally; egg quality is tied to age, not AMH pool size.
Oral contraceptive pills (OCPs) can artificially suppress AMH levels. If a patient gets an AMH tested while on the pill, the result is falsely terrifying.

Next Steps

Obstetric Management of IVF Pregnancies

01
Continue progesterone supplementation through 10-12 weeks until the placenta takes over production (corpus luteum rescue).
02
Schedule a viability ultrasound at 7-8 weeks.
03
Offer fetal echocardiogram at 20-22 weeks due to the slightly increased background risk of congenital heart defects in IVF/ICSI neonates.
04
Monitor for preeclampsia (IVF with frozen embryo transfer strongly correlates with higher risk of hypertensive disorders of pregnancy).

The Evidence

ACOG Guidelines

Methods for Estimating the Due Date.

ACOG Committee Opinion No. 700. • Obstet Gynecol.. 2017;Explicitly mandates that pregnancies conceived with Assisted Reproductive Technology must be dated exclusively by the embryonic age and transfer date, disregarding LMP and early ultrasound.

Origins & History

Historical Context

The absolute precision of IVF dating revolutionized modern obstetrics, allowing clinicians to bypass the inherent unreliability of maternal menstrual history and identifying cases of true fetal growth restriction (FGR) with perfect denominators.

Last Comprehensive Review: 2026-07-17

In Recent Clinical News

Scanning Medical Journals

No new significant updates or guidelines matching this topic were found today. We will check again soon.