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Fetal Anemia (MCA PSV)

MCA Peak Systolic Velocity

Fetal Anemia Surveillance (Mari et al.)

PSV (cm/s)

Weeks (GA)

Clinical Note: MCA-PSV > 1.5 MoM is the evidence-based threshold for invasive testing (cordocentesis) or intrauterine transfusion in alloimmunized pregnancies.

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

Primary Clinical Uses

Non-invasive screening for suspected fetal anemia (e.g., Rh/Kell alloimmunization)

Monitoring pregnancies at high risk for parvovirus B19 infection

Surveillance in cases of suspected twin-anemia polycythemia sequence (TAPS)

When NOT to Use

Predictive value drops precipitously after 35 weeks of gestation. Do NOT use MCA-PSV as the sole determinant for delivery timing in late preterm/term fetuses. False positive rates surge near term.

Last Comprehensive Review: 2026