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Clinical Notice:OpiCalc is not a substitute for professional clinical judgment. Always verify dosages and guidelines.

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Gail Model Breast Risk

Gail Model Breast Risk

Breast Cancer Risk Assessment Tool (BCRAT)

Note: The Gail Model is most accurate for women over 35 without a personal history of LCIS or DCIS. A 5-year risk ≥ 1.67% is considered "high risk" and may justify chemoprevention.

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

Primary Clinical Uses

Estimating the 5-year and lifetime risk of developing invasive breast cancer in women aged 35 years and older.
Determining eligibility for prophylactic breast cancer risk-reducing medications (Tamoxifen/Raloxifene).
Triaging patients for enhanced screening protocols (e.g., adjunctive Breast MRI).

Exclusion Criteria

This tool is useless and invalid for patients with known BRCA1/BRCA2 genetic mutations, patients with a history of Lobular/Ductal Carcinoma In Situ (LCIS/DCIS), or those who have received prior medical radiation to the chest.

Last Comprehensive Review: 2026