ACL Graft Choice Risk Factors ACL-RSI Calculator (Return to Sport Readiness)AHA Pre-Participation Screening AOFAS Ankle-Hindfoot Scale ASES Elbow Score ASES Shoulder Score Acute:Chronic Workload Ratio (ACWR)Altitude Gain Guidelines Ankle Syndesmosis (High Ankle Sprain)Athlete's Heart vs HCM Beighton Score (Joint Hypermobility)Borg CR-10 Scale Borg RPE Scale (6–20)Brighton Criteria (BJHS)Buffalo Concussion Treadmill Test (BCTT)Child SCAT6 (Age 8–12)Commotio Cordis Protocol Cumberland Ankle Instability Tool (CAIT)DASH (UE Disability Index)Doha Groin Agreement ESC HCM SCD Risk Score ESC Pre-Participation Screening Energy Availability Calculator FAI Syndrome (Warwick)FAOS (Foot and Ankle Outcome Score)Fear-Avoidance Beliefs Questionnaire (FABQ)Female Athlete Triad Risk Foot Posture Index (FPI-6)Foot and Ankle Ability Measure (FAAM)Functional Movement Screen (FMS)Graduated Return-to-Play (GRTP) Protocol HAGOS (Hip and Groin Outcome Score)Hamstring Asymmetry Index Heat Index (Apparent Temp)Hip Outcome Score (HOS)Hooper Index (Athlete Wellness)I-PRRS (Psychological Readiness)IKDC (Objective Examination)IKDC (Subjective Knee Evaluation)Injury Severity KJOC Shoulder & Elbow Score KOOS (Knee Outcome Score)KOOS-PS (Physical Function Short Form)Kujala (Anterior Knee Pain Scale)LEAF-Q (LEA Screening)Lake Louise AMS Score Limb Symmetry Index (LSI)Little League Elbow Grading Lysholm Knee Score Marx Activity Rating Scale (MARS)Mayo Elbow Performance Score (MEPS)Modified Schober Test NEXUS C-Spine Criteria Neck Disability Index (NDI)One-Rep Max Estimator Osgood-Schlatter Severity Oswestry Disability Index (ODI)Ottawa Knee Rules Oxford Elbow Score Oxford Shoulder Score PAR-Q+ Readiness Questionnaire PARS-3 Youth Readiness Patellar Instability Severity Score Pitch Smart Guidelines (USA Baseball)Pittsburgh Knee Rules Post-Concussion Symptom Scale (PCSS)QuickDASH (Shoulder & UE)RED-S CAT (Clinical Assessment)Re-injury Anxiety Inventory (RIAI)Relative Age Effect (RAE)Return-to-Play Battery SANE Score (Single Assessment)SCAT6 (Sport Concussion Assessment Tool 6)SCOAT6 (Sub-acute and Office Follow-up)SEAQ-I Appetite Questionnaire STarT Back Screening Tool Session RPE (Internal Load)Sever's Disease Activity Single-Leg Hop Test Battery Standardized Assessment of Concussion (SAC)Steroid Equivalence Calculator Stinger / Burner Grading Sweat Rate and Rehydration TSK-11 (Tampa Scale for Kinesiophobia)TUE Criteria Checklist Tanner Stage Assessment Tegner Activity Scale (TAS)Training Monotony and Strain UCL Injury Risk (Medial Elbow)VISA-A (Achilles Tendinopathy)VISA-P Scale (Patellar Tendinopathy)VO2 Max VOMS (Vestibular/Ocular-Motor Screening)WADA Prohibited List Checker WBGT (Wet Bulb Globe Temp)WORC (Rotator Cuff Index)WOSI (Shoulder Instability Index)Wilks Score (Relative Strength)Wind Chill Index hEDS Diagnostic Criteria (2017)iHOT-33 (International Hip Outcome Tool)

Recent Journal Updates

British J Clinical PharmacologyJun 26, 2026

Pharmacogenetic CYP2B6 variants affect steroid hormone metabolism in human breast cancer cells

Clinical Context

We think this might be relevant to the clinical guidance for Steroid Equivalence.

British J HaematologyJun 16, 2026

Clinical and immunological effects of adding cyclophosphamide to pomalidomide–dexamethasone in relapsed‐refractory multiple myeloma: The randomized MUKseven trial

Clinical Context

We think this has broad domain relevance to Steroid Equivalence.

PLOS MedicineJun 4, 2026

Beyond associations: Navigating the safety of non-steroidal anti-inflammatory drugs (NSAIDs) in early pregnancy

Clinical Context

We think this might be relevant to the clinical guidance for Steroid Equivalence.

Steroid Equivalence Calculator

Corticosteroid Equivalence

hydrocortisone

20.00mg

prednisone

5.00mg

prednisolone

5.00mg

methylprednisolone

4.00mg

triamcinolone

4.00mg

dexamethasone

0.75mg

betamethasone

0.60mg

Conversions are based on glucocorticoid (anti-inflammatory) potency. Mineralocorticoid potency varies significantly (e.g., Fludrocortisone). WADA Warning: Systemic administration is prohibited in-competition. Local injections may require TUE or Therapeutic Use Notification (TUN) depending on specific rules.

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

Converting between different glucocorticoid formulations for therapeutic equivalence in chronic inflammatory conditions (e.g., rheumatoid arthritis, asthma, inflammatory bowel disease).

Adjusting corticosteroid doses when switching routes of administration (oral, intravenous, intra-articular, topical).

Calculating cumulative steroid exposure to assess risk of adverse effects (osteoporosis, adrenal suppression, hyperglycemia).

Standardizing reporting in clinical trials and observational studies involving corticosteroid therapy.

Guiding perioperative steroid coverage for patients on chronic glucocorticoid therapy undergoing surgery.

Assessing relative potency in sports medicine for athletes using corticosteroids for injury management (e.g., intra-articular injections).

Key Indication - Therapeutic Equivalence Conversion

The primary clinical utility of steroid equivalence is to ensure safe and effective dose conversion when switching between different glucocorticoid preparations. This is critical to avoid underdosing (loss of disease control) or overdosing (increased toxicity). The conversion factors are based on relative anti-inflammatory potency and mineralocorticoid activity, as established by endocrinology guidelines (e.g., Endocrine Society). For example, 1 mg of dexamethasone is equivalent to approximately 6.67 mg of prednisone.

When Not to Use / Contraindications

Do not use for acute adrenal crisis management; hydrocortisone is preferred due to its rapid onset and mineralocorticoid activity.

Not applicable for topical or inhaled corticosteroids without specific conversion tables that account for bioavailability and local potency.

Avoid reliance on equivalence tables for intra-articular corticosteroids; local potency and solubility differ significantly from systemic equivalents.

Not suitable for patients with known hypersensitivity to specific glucocorticoid formulations.

Do not use as a substitute for clinical judgment in patients with hepatic or renal impairment, as metabolism and clearance may alter equivalence.

Last Comprehensive Review: 2026

Recent Journal Updates

British J Clinical PharmacologyJun 26, 2026

Pharmacogenetic CYP2B6 variants affect steroid hormone metabolism in human breast cancer cells

Clinical Context

We think this might be relevant to the clinical guidance for Steroid Equivalence.

British J HaematologyJun 16, 2026

Clinical and immunological effects of adding cyclophosphamide to pomalidomide–dexamethasone in relapsed‐refractory multiple myeloma: The randomized MUKseven trial

Clinical Context

We think this has broad domain relevance to Steroid Equivalence.

PLOS MedicineJun 4, 2026

Beyond associations: Navigating the safety of non-steroidal anti-inflammatory drugs (NSAIDs) in early pregnancy

Clinical Context

We think this might be relevant to the clinical guidance for Steroid Equivalence.

Steroid Equivalence Calculator

Corticosteroid Equivalence

hydrocortisone

20.00mg

prednisone

5.00mg

prednisolone

5.00mg

methylprednisolone

4.00mg

triamcinolone

4.00mg

dexamethasone

0.75mg

betamethasone

0.60mg

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

Converting between different glucocorticoid formulations for therapeutic equivalence in chronic inflammatory conditions (e.g., rheumatoid arthritis, asthma, inflammatory bowel disease).

Adjusting corticosteroid doses when switching routes of administration (oral, intravenous, intra-articular, topical).

Calculating cumulative steroid exposure to assess risk of adverse effects (osteoporosis, adrenal suppression, hyperglycemia).

Standardizing reporting in clinical trials and observational studies involving corticosteroid therapy.

Guiding perioperative steroid coverage for patients on chronic glucocorticoid therapy undergoing surgery.

Assessing relative potency in sports medicine for athletes using corticosteroids for injury management (e.g., intra-articular injections).

Key Indication - Therapeutic Equivalence Conversion

When Not to Use / Contraindications

Do not use for acute adrenal crisis management; hydrocortisone is preferred due to its rapid onset and mineralocorticoid activity.

Not applicable for topical or inhaled corticosteroids without specific conversion tables that account for bioavailability and local potency.

Avoid reliance on equivalence tables for intra-articular corticosteroids; local potency and solubility differ significantly from systemic equivalents.

Not suitable for patients with known hypersensitivity to specific glucocorticoid formulations.

Do not use as a substitute for clinical judgment in patients with hepatic or renal impairment, as metabolism and clearance may alter equivalence.

Last Comprehensive Review: 2026