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ICP-based Cerebral Perfusion Pressure (CPP) Calculator

Neuro-Critical Care

Input Parameters

Mean Arterial Pressure (MAP)mmHg

Intracranial Pressure (ICP)mmHg

Awaiting Data

Enter the patient's MAP and ICP to calculate the cerebral perfusion pressure.

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

When to Use CPP Monitoring

Severe traumatic brain injury (TBI) with GCS ≤ 8

Patients with invasive intracranial pressure (ICP) monitoring in ICU

Diffuse cerebral edema or intracranial hemorrhage

Post-neurosurgical patients requiring neurocritical care

Suspected raised intracranial pressure (ICP)

Hemodynamically unstable TBI requiring vasopressor support

Clinical Role in Neurotrauma

Parameter	Physiologic Role	Clinical Importance
ICP	Intracranial pressure	Reflects brain swelling / mass effect
MAP	Systemic perfusion pressure	Driving force for cerebral blood flow
CPP	Net cerebral perfusion	Key determinant of brain oxygen delivery

Limitations

Requires invasive ICP monitoring (external ventricular drain or intraparenchymal probe)

Does not directly measure cerebral oxygenation

Affected by systemic hypotension and vasopressor use

Autoregulation may be impaired in severe TBI

Single value may be misleading without trends

Last Comprehensive Review: 2026

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