AAST Bladder Injury Scale AAST Bowel Injury Scale AAST Cardiac Injury Scale AAST Diaphragm Injury Scale AAST Hepatic Injury Scale AAST Kidney Injury Scale AAST Lung Injury Scale AAST Pancreatic Injury Scale AAST Rectal Injury Scale AAST Splenic Injury Scale AAST Vascular Injury Scale ABC Score (Massive Transfusion)ACS COT Field Triage Guidelines ATLS Hemorrhagic Shock Classification Abbreviated Injury Scale (AIS)Ankle-Brachial Index (ABI) in Trauma Base Deficit in Trauma Brain Injury Guidelines (BIG) Score Cardiac Wound Index Chest Trauma Score (CTS)Damage Control Decision Score (DCDS)Denver Criteria (BCVI)Esophageal Perforation Severity Score (PSS)Expanded Denver Criteria (BCVI)Flint Colon Injury Scale Frailty Index in Trauma (mFI-5)Geriatric Trauma Outcome Score (GTOS)Hard Signs of Vascular Injury Checklist Hemorrhage Control Decision Aid (Wound Packing vs. Tourniquet)ICP-based Cerebral Perfusion Pressure (CPP) Calculator Injury Severity Score (ISS)Injury Severity Score — Age-adjusted (ISS-Age)Lethal Triad / Trauma Triad of Death Calculator Limb Salvage Index (LSI)Mangled Extremity Severity Score (MESS)Mechanism, Glasgow Coma Scale, Age, and Arterial Pressure (MGAP)Memphis Criteria (BCVI)Modified Shock Index (MSI)Nerve Injury, Ischemia, Soft-tissue, Skeletal Injury, Shock, Age (NISSSA)New Injury Severity Score (NISS)Open Abdomen Classification (Björck)Pediatric Trauma Score (PTS)Pelvic Trauma Hemorrhage Risk Score Penetrating Abdominal Trauma Index (PATI)Physiologic Extreme Emergency in Trauma (FEET)Predictive Salvage Index (PSI)REBOA Zone Selection Guide Resuscitative Thoracotomy Indications (EAST/WTA Guidelines)Revised Trauma Score (RTS)RibScore Shock Index (SI)TASH Score TRISS Index Thoracic Trauma Severity Score (TTS)Tile Classification of Pelvic Fractures Trauma and Injury Severity Score — Pediatric (PTS)Young–Burgess Pelvic Fracture Classification

Injury Severity Score (ISS)

Anatomical Severity Scoring

Regional AIS Scores (0-6)

Head & Neck

Face

Chest / Thorax

Abdomen / Pelvis

Extremities

External / Skin

Select Regional Scores

Assign the highest Abbreviated Injury Scale (AIS) value for each region to determine the patient's overall trauma severity.

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

The Injury Severity Score (ISS) is an anatomical scoring system that provides an overall score for patients with multiple injuries. It is the gold standard for trauma research, quality assurance, and benchmarking trauma center performance.

Limitation	Description
Anatomic Focus	Does not account for physiological derangement (BP, GCS)
Single-Region Heavy	Ignores a second severe injury in the same body region
Geriatric Bias	Underestimates mortality in patients > 65 years
Subjectivity	Requires expert coding of the Abbreviated Injury Scale (AIS)

Last Comprehensive Review: 2026

Related Tools

Abbreviated Injury Scale

Nerve Injury, Ischemia, Soft-tissue, Skeletal Injury, Shock, Age

Revised Trauma Score

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