What are the limitations of the fludrocortisone suppression test interpreter?

While the fludrocortisone suppression test interpreter is highly validated, it should not replace clinical judgment. OpiCalc provides the latest evidence-based limitations for the fludrocortisone suppression test interpreter to ensure safe bedside use and optimal diagnostic accuracy.

How does the fludrocortisone suppression test interpreter compare to other Endocrinology scores?

The fludrocortisone suppression test interpreter is a gold-standard diagnostic tool. OpiCalc provides side-by-side clinical guidance to help clinicians choose the most specific evidence-based tool for their patient's presentation.

Is the fludrocortisone suppression test interpreter free to use?

Yes. OpiCalc provides the fludrocortisone suppression test interpreter completely ad-free and optimized for mobile bedside use, ensuring you can calculate medical risk swiftly and without distraction.

Evidence-Based Fludrocortisone suppression test interpreter Scoring

CLINICAL REFERENCE

CLINICAL INSIGHT

When to Use

Confirmatory testing in patients with high screening ARR (Aldosterone-to-Renin Ratio).
When salt loading test is contraindicated or inconclusive.
Identifying autonomy of aldosterone production in Primary Aldosteronism (PA).

CLINICAL INSIGHT

How it Works

Standard FST Procedure

Days 1–4: Fludrocortisone 0.1 mg every 6 hours.
Sodium Loading: Goal urinary sodium > 200 mEq/day (via pills or diet).
Potassium: Maintain serum K+ > 3.0 mEq/L with supplementation.
Day 4 (10 AM): Measure upright Plasma Aldosterone and Renin (PRA/DRC).

CLINICAL INSIGHT

Practical Pearls

Diagnostic Thresholds

Aldo (ng/dL)	Interpretation
> 6.0	Positive (PA Confirmed)
< 6.0	Negative (Excludes PA)

Potassium Caveat

Hypokalaemia is a potent inhibitor of aldosterone secretion. If a patient is hypokalaemic during the test, they may "pseudo-suppress" their aldosterone, leading to a false-negative result. Aggressive potassium supplementation is essential during the 4-day protocol.

CLINICAL INSIGHT

Evidence Base

Guidelines

The management of primary aldosteronism: case detection, diagnosis, and treatment: an Endocrine Society Clinical Practice Guideline.

Funder JW, Carey RM, et al.J Clin Endocrinol Metab2016

When to Use

When to Use

How it Works

Standard FST Procedure

Practical Pearls

Diagnostic Thresholds

Potassium Caveat

Evidence Base

Guidelines

Fludrocortisone Suppression Test Interpreter

When to Use

When to Use

How it Works

Standard FST Procedure

Practical Pearls

Diagnostic Thresholds

Potassium Caveat

Evidence Base

Guidelines

Fludrocortisone Suppression Test Interpreter

Clinical Evidence and Methodology

When to Use

When to Use

How it Works

Standard FST Procedure

Practical Pearls

Diagnostic Thresholds

Potassium Caveat

Evidence Base

Guidelines

Fludrocortisone Suppression Test Interpreter

Clinical Evidence and Methodology

When to Use

When to Use

How it Works

Standard FST Procedure

Practical Pearls

Diagnostic Thresholds

Potassium Caveat

Evidence Base

Guidelines

Fludrocortisone Suppression Test Interpreter