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Calculate Insulin infusion rate calculator dka | CMS & Clinical Guidelines

CLINICAL REFERENCE

CLINICAL INSIGHT

When to Use

Management of Diabetic Ketoacidosis (DKA) in adults.
Initial management of Hyperosmolar Hyperglycaemic State (HHS) if ketones are present or insulin is required for glycaemic control.
Note: Only use Regular (short-acting) insulin IV.

CLINICAL INSIGHT

How it Works

Option A: Bolus + Infusion

Bolus: 0.1 units/kg Body Weight (IV).
Infusion: 0.1 units/kg/hr (IV Regular Insulin).

Option B: Infusion Only

Bolus: None.
Infusion: 0.14 units/kg/hr (IV Regular Insulin).

CLINICAL INSIGHT

Practical Pearls

Rate of Decline

The goal is a BG decline of 50–75 mg/dL per hour. If this is not achieved, increase the insulin infusion rate by 1 unit/hr every hour until a steady decline is reached.

When to Add Dextrose

When blood glucose reaches 200 mg/dL (DKA) or 300 mg/dL (HHS), reduce the insulin infusion rate to 0.02–0.05 units/kg/hr and add D5W to the maintenance fluids to prevent hypoglycemia while allowing the ketones to clear.

CLINICAL INSIGHT

Evidence Base

Primary Source

Hyperglycemic crises in adult patients with diabetes.

Kitabchi AE, Umpierrez GE, et al.Diabetes Care2009

When to Use

When to Use

How it Works

Option A: Bolus + Infusion

Option B: Infusion Only

Practical Pearls

Rate of Decline

When to Add Dextrose

Evidence Base

Primary Source

Insulin Infusion Rate Calculator (DKA)

When to Use

When to Use

How it Works

Option A: Bolus + Infusion

Option B: Infusion Only

Practical Pearls

Rate of Decline

When to Add Dextrose

Evidence Base

Primary Source

Insulin Infusion Rate Calculator (DKA)

Clinical Evidence and Methodology

When to Use

When to Use

How it Works

Option A: Bolus + Infusion

Option B: Infusion Only

Practical Pearls

Rate of Decline

When to Add Dextrose

Evidence Base

Primary Source

Insulin Infusion Rate Calculator (DKA)

Clinical Evidence and Methodology

When to Use

When to Use

How it Works

Option A: Bolus + Infusion

Option B: Infusion Only

Practical Pearls

Rate of Decline

When to Add Dextrose

Evidence Base

Primary Source

Insulin Infusion Rate Calculator (DKA)