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Recent Journal Updates

DiabetologiaJun 6, 2026
Time-restricted eating versus dietetic guidance on glycaemic outcomes in adults at risk of type 2 diabetes: a non-inferiority randomised clinical trial

Clinical Context

We think this has broad domain relevance to Biplane Simpson EF.

DiabetologiaJun 6, 2026
Plasma small RNA profiling reveals a three-miRNA signature associated with early beta cell dysfunction across glucose tolerance stages

Clinical Context

We think this has broad domain relevance to Biplane Simpson EF.

Intensive Care MedicineJun 2, 2026
Nutrition support in the ICU: current evidence and evolving standards

Clinical Context

We think this has broad domain relevance to Biplane Simpson EF.

Biplane Simpson EF

Biplane Simpson EF: LV ejection fraction from apical 2- and 4-chamber disk summation method.

Formula

EF = (avg EDV − avg ESV) / avg EDV × 100%

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

When to Use

Primary LV systolic function assessment on transthoracic echo
HF diagnosis and severity stratification
Post-MI LV function assessment
Cardiotoxicity monitoring (chemotherapy, HER2 inhibitors)
Serial monitoring in LVAD candidates
More accurate than M-mode (Teichholz) in most patients

Key Advantages

Less dependent on geometric assumptions vs. M-mode
Validated against cardiac MRI gold standard
Incorporates regional function variations
Recommended by ESC/AHA guidelines as primary measurement
Reproducible across operators with good image quality

Last Comprehensive Review: 2026

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

When to Use

Primary LV systolic function assessment on transthoracic echo
HF diagnosis and severity stratification
Post-MI LV function assessment
Cardiotoxicity monitoring (chemotherapy, HER2 inhibitors)
Serial monitoring in LVAD candidates
More accurate than M-mode (Teichholz) in most patients

Key Advantages

Less dependent on geometric assumptions vs. M-mode
Validated against cardiac MRI gold standard
Incorporates regional function variations
Recommended by ESC/AHA guidelines as primary measurement
Reproducible across operators with good image quality

Last Comprehensive Review: 2026

Related Cardiovascular Tools

Framingham 10-Year Risk
REVEAL 2.0 Score
Teichholz Formula
LV Mass Index
MAGGIC Risk Score
ABCD2 Score
EDACS Score
EHRA Score
Cardiac Output Index
Brugada Criteria
Cardiovascular CalculatorsCritical Care CalculatorsEmergency Medicine Calculators
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