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Recent Journal Updates

Cancer MedicineJun 5, 2026

Bone Marrow Failure Model Mimics Aplastic Anemia Patients: Single‐Cell Landscape of Immune Response Reveals Novel Mechanisms of Immune Imbalance in AA

Clinical Context

We think this has broad domain relevance to Wilkins Score (Mitral Valvuloplasty).

FDA MedWatchJun 3, 2026

UPDATE: Hintermann Series H3 Total Ankle Replacement Has a Higher-Than-Expected Risk of Device Failure: FDA Safety Communication

Clinical Context

We think this has broad domain relevance to Wilkins Score (Mitral Valvuloplasty).

Wilkins Score

Wilkins Score (Mitral Valvuloplasty): Echocardiographic score used to predict the outcome of PMBV in patients with Rheumatic Mitral Stenosis.

1. Mobility

2. Leaflet Thickening

3. Subvalvular Thickening

4. Calcification

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

Assessment of Rheumatic Mitral Stenosis (MS) suitability for Percutaneous Mitral Balloon Valvuloplasty (PMBV).

To predict the immediate result and long-term durability of the valvuloplasty procedure.

Absolute Contraindications to PMBV

Presence of Left Atrial (LA) thrombus or Moderate-to-Severe Mitral Regurgitation (MR). Even if the Wilkins score is low, these findings preclude the percutaneous approach.

Last Comprehensive Review: 2026

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

Assessment of Rheumatic Mitral Stenosis (MS) suitability for Percutaneous Mitral Balloon Valvuloplasty (PMBV).

To predict the immediate result and long-term durability of the valvuloplasty procedure.

Absolute Contraindications to PMBV

Presence of Left Atrial (LA) thrombus or Moderate-to-Severe Mitral Regurgitation (MR). Even if the Wilkins score is low, these findings preclude the percutaneous approach.

Last Comprehensive Review: 2026

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Vancouver Chest Pain Rule

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TIMI

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