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Recent Journal Updates

Drug SafetyJun 2, 2026
Gabapentin and Pregabalin Use in First Trimester of Pregnancy and Risk of Specific Congenital Anomalies: An IMI ConcePTION European Case-Malformed Control Study

Clinical Context

We think this might be relevant to the clinical guidance for HEART Score — Chest Pain Risk Stratification.

WHO NewsMay 31, 2026
Joint statement by the Government of the Democratic Republic of the Congo and WHO concerning the outbreak of Ebola disease caused by the Bundibugyo virus

Clinical Context

We think this might be relevant to the clinical guidance for HEART Score — Chest Pain Risk Stratification.

FDA MedWatchMay 27, 2026
Early Alert: Heart Pump Issue from Abiomed

Clinical Context

We think this might be relevant to the clinical guidance for HEART Score — Chest Pain Risk Stratification.

HEART Score

Validated for ED chest pain triage

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

When to Use

Risk stratification of patients ≥18 years presenting to the Emergency Department with chest pain.
Assessing the probability of Major Adverse Cardiac Events (MACE) within 6 weeks.
Identifying low-risk patients suitable for early discharge without bedside observation or immediate provocative testing.

When NOT to Use

New ST-segment elevation (STEMI): These patients require immediate reperfusion.
Hemodynamic instability or obvious alternative life-threatening diagnosis (e.g., tension pneumothorax).
Patients with new, clearly ischemic ECG changes (ST-depression ≥1mm).

Last Comprehensive Review: 2026

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