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Modified Sgarbossa Criteria

Modified Sgarbossa: Identifies acute MI in patients with LBBB or Ventricular Paced rhythms.

Concordant ST Elevation ≥ 1mm

ST elevation in a lead with a positive QRS complex (most specific).

Concordant ST Depression ≥ 1mm in V1-V3

ST depression in leads with negative QRS (V1, V2, or V3).

Discordant ST/S ratio ≤ -0.25

Excessive discordance: ST elevation height / S wave depth ≤ -0.25 (Modified Smith criterion).

Guidelines & Evidence

Verified

Last Review: 2026-07-17

When to Use

When to Use

Evaluation of suspected Acute Myocardial Infarction in the presence of LBBB.
Proposed as a more sensitive alternative to the original Sgarbossa criteria.

How it Works

Smith’s Modification

The original 3rd Sgarbossa criterion (≥ 5mm discordant ST elevation) was found to be poor at discriminating AMI. Smith modified this to a proportional rule.

The S/T Ratio

ST elevation / S-wave amplitude ≤ −0.25 In other words, discordant ST elevation that is at least 25% of the preceding S-wave depth is considered a positive sign of MI.

Clinical Pearls

Sensitivity Boost

The modified criteria increase sensitivity from ~20-30% to ~80% while maintaining high specificity (~99%). It is now widely recommended over the original criteria in emergency medicine.

Next Steps

Complementary Calculators

Sgarbossa Criteria
HEART Score (Chest Pain)
GRACE ACS Risk Score
TIMI Risk Score (STEMI)
Killip Classification

The Evidence

Validation Study

Diagnosis of ST-elevation myocardial infarction in the presence of left bundle branch block with the ST-elevation to S-wave ratio in a modified Sgarbossa rule.

Smith SW et al. • Ann Emerg Med.. 2012;60(6):766–76. Validated the −0.25 ratio threshold.

Last Comprehensive Review: 2026-07-17

Guidelines & Evidence

Verified

Last Review: 2026-07-17

When to Use

When to Use

Evaluation of suspected Acute Myocardial Infarction in the presence of LBBB.
Proposed as a more sensitive alternative to the original Sgarbossa criteria.

How it Works

Smith’s Modification

The original 3rd Sgarbossa criterion (≥ 5mm discordant ST elevation) was found to be poor at discriminating AMI. Smith modified this to a proportional rule.

The S/T Ratio

ST elevation / S-wave amplitude ≤ −0.25 In other words, discordant ST elevation that is at least 25% of the preceding S-wave depth is considered a positive sign of MI.

Clinical Pearls

Sensitivity Boost

The modified criteria increase sensitivity from ~20-30% to ~80% while maintaining high specificity (~99%). It is now widely recommended over the original criteria in emergency medicine.

Next Steps

Complementary Calculators

Sgarbossa Criteria
HEART Score (Chest Pain)
GRACE ACS Risk Score
TIMI Risk Score (STEMI)
Killip Classification

The Evidence

Validation Study

Diagnosis of ST-elevation myocardial infarction in the presence of left bundle branch block with the ST-elevation to S-wave ratio in a modified Sgarbossa rule.

Smith SW et al. • Ann Emerg Med.. 2012;60(6):766–76. Validated the −0.25 ratio threshold.

Last Comprehensive Review: 2026-07-17

Recent Journal Updates

British J Clinical PharmacologyJul 22, 2026
CHATD Questionnaire: Development, Validation and Evaluation of Child and Parent Attitudes Towards Deprescribing

Clinical Context

We think this has broad domain relevance to Modified Sgarbossa Criteria.

JAMAJul 21, 2026
Correction to Primary Composite Outcome in a Trial of Transfusion Strategy

Clinical Context

We think this has broad domain relevance to Modified Sgarbossa Criteria.

PLOS MedicineJul 21, 2026
Optimising scale-up of injectable lenacapavir for HIV pre-exposure prophylaxis in South Africa: A modelling study and economic evaluation

Clinical Context

We think this has broad domain relevance to Modified Sgarbossa Criteria.