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Recent Journal Updates

DiabetologiaJun 6, 2026
Plasma small RNA profiling reveals a three-miRNA signature associated with early beta cell dysfunction across glucose tolerance stages

Clinical Context

We think this has broad domain relevance to HAS-BLED Score for Bleeding Risk.

JAMAJun 2, 2026
Can Multicancer Detection Blood Tests Save Lives?

Clinical Context

We think this has broad domain relevance to HAS-BLED Score for Bleeding Risk.

DiabetologiaMay 22, 2026
Age-related patterns of cardiometabolic risk factors for complications in type 2 diabetes

Clinical Context

We think this has broad domain relevance to HAS-BLED Score for Bleeding Risk.

HAS-BLED

Major bleeding risk in AF • ESC / AHA Guidelines

Ready for Assessment

Select clinical factors to estimate annual major bleed risk.

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

Clinical Utility

Estimation of 1-year risk of major bleeding in adults with non-valvular atrial fibrillation.
Decision support for managing patients on Oral Anticoagulation (OAC) therapy.
Identifying modifiable bleeding risk factors to optimize patient safety.

Defining "Major Bleeding"

Major bleeding is typically defined as intracranial hemorrhage, bleeding requiring hospitalization, a drop in hemoglobin > 2 g/dL, or the need for blood transfusion.

Related Scores in Practice

In clinical practice, this assessment is frequently evaluated alongside other validated measures. Depending on the patient's presentation and specific diagnostic requirements, you may also need to utilize the CHA2DS2-VASc, ORBIT Score, ABC-AF Bleeding Score, CHADS2, HEMORR2HAGES, eGFR (CKD-EPI) or the Creatinine Clearance Multi-Method to formulate a comprehensive care plan.

Last Comprehensive Review: 2026

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