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MAGGIC Risk Score

MAGGIC Risk Score: Validated predictor of mortality in patients with Heart Failure (both HFrEF and HFpEF).

Male Gender
Diabetes Melitus
COPD
HF Diagnosis > 18 months ago
Current Smoker
Taking Beta-Blocker
Taking ACEi / ARB
Guidelines & Evidence

Verified

Last Review: 2026-07-17

When to Use

When to Use

Prognostication of mortality in patients with chronic heart failure.
Validated for both Heart Failure with Reduced Ejection Fraction (HFrEF) and Heart Failure with Preserved Ejection Fraction (HFpEF).
To guide clinical decision-making and patient counseling regarding long-term survival.

How it Works

Key Variables

Age and Sex
LVEF (Ejection Fraction)
NYHA Functional Class
Serum Creatinine
Body Mass Index (BMI)
Systolic BP
Smoking Status
Diabetes
COPD
Medications (ACEi/ARB, Beta-blockers)

Biological Basis

The MAGGIC score was derived from a meta-analysis of 30 studies (n=39,372). It is often considered more robust than the Seattle Heart Failure Model because it was derived from a much larger and more diverse dataset that included HFpEF patients.

Clinical Pearls

MAGGIC vs. Seattle

While the Seattle model is excellent for showing the impact of specific medications, MAGGIC is often preferred for its simplicity and its inclusion of HFpEF patients, who make up a significant portion of the modern heart failure population.

Next Steps

Complementary Calculators

Seattle Heart Failure Model (SHFM)
H2FPEF Score
EHMRG Score
NT-proBNP Age-Adjusted Thresholds
GWTG-HF Score

The Evidence

Primary Derivation

Predicting survival in heart failure: a risk score based on 39 372 patients from 30 studies.

Pocock SJ et al. • Eur Heart J.. 2013;n=39,372. The largest individual-patient data meta-analysis of heart failure mortality.

Last Comprehensive Review: 2026-07-17

Guidelines & Evidence

Verified

Last Review: 2026-07-17

When to Use

When to Use

Prognostication of mortality in patients with chronic heart failure.
Validated for both Heart Failure with Reduced Ejection Fraction (HFrEF) and Heart Failure with Preserved Ejection Fraction (HFpEF).
To guide clinical decision-making and patient counseling regarding long-term survival.

How it Works

Key Variables

Age and Sex
LVEF (Ejection Fraction)
NYHA Functional Class
Serum Creatinine
Body Mass Index (BMI)
Systolic BP
Smoking Status
Diabetes
COPD
Medications (ACEi/ARB, Beta-blockers)

Biological Basis

The MAGGIC score was derived from a meta-analysis of 30 studies (n=39,372). It is often considered more robust than the Seattle Heart Failure Model because it was derived from a much larger and more diverse dataset that included HFpEF patients.

Clinical Pearls

MAGGIC vs. Seattle

While the Seattle model is excellent for showing the impact of specific medications, MAGGIC is often preferred for its simplicity and its inclusion of HFpEF patients, who make up a significant portion of the modern heart failure population.

Next Steps

Complementary Calculators

Seattle Heart Failure Model (SHFM)
H2FPEF Score
EHMRG Score
NT-proBNP Age-Adjusted Thresholds
GWTG-HF Score

The Evidence

Primary Derivation

Predicting survival in heart failure: a risk score based on 39 372 patients from 30 studies.

Pocock SJ et al. • Eur Heart J.. 2013;n=39,372. The largest individual-patient data meta-analysis of heart failure mortality.

Last Comprehensive Review: 2026-07-17

Recent Journal Updates

JAMAJul 21, 2026
Correction to Primary Composite Outcome in a Trial of Transfusion Strategy

Clinical Context

We think this might be relevant to the clinical guidance for MAGGIC Risk Score (Heart Failure).

FDA MedWatchJul 15, 2026
Early Alert: Ventilator Issue from Resmed

Clinical Context

We think this might be relevant to the clinical guidance for MAGGIC Risk Score (Heart Failure).

FDA MedWatchJul 2, 2026
Heart Pump Recall: Abiomed Removes Impella CP Sets with SmartAssist

Clinical Context

We think this might be relevant to the clinical guidance for MAGGIC Risk Score (Heart Failure).