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Sgarbossa Criteria

Sgarbossa Criteria: Used to identify acute myocardial infarction (AMI) in the presence of Left Bundle Branch Block (LBBB) or ventricular paced rhythm. A score ≥ 3 is highly specific for AMI.

Criteria Assessment

Guidelines & Evidence

Verified

Last Review: 2026-07-17

When to Use

When to Use

Evaluation of suspected Acute Myocardial Infarction (AMI) in patients with a Left Bundle Branch Block (LBBB).
To differentiate baseline LBBB ST-changes from acute ischemia.
In patients with ventricularly paced rhythms (pacemaker).

How it Works

The Rule of Discordance

In normal LBBB, the ST segment and T wave should be "discordant" (opposite) to the main QRS deflection. Sgarbossa criteria identify AMI by looking for "concordance" (ST deviation in the same direction as the QRS) or "excessive discordance."

Scoring Criteria

Concordant ST elevation ≥ 1 mm in any lead5 pts
Concordant ST depression ≥ 1 mm in lead V1, V2, or V33 pts
Discordant ST elevation ≥ 5 mm in leads with negative QRS2 pts

Interpretation

A score ≥ 3 has a specificity of ~98% for AMI, though sensitivity is low (~20-30%).

Clinical Pearls

LBBB = STEMI?

Recent ESC and AHA guidelines no longer consider "new LBBB" alone as a STEMI equivalent unless symptoms are refractory. Sgarbossa criteria help identify the subset of LBBB patients who truly have an occluded artery and need the cath lab.

Next Steps

Complementary Calculators

Modified Sgarbossa Criteria
HEART Score (Chest Pain)
GRACE ACS Risk Score
TIMI Risk Score (STEMI)
Killip Classification

The Evidence

Original Study

Electrocardiographic diagnosis of evolving acute myocardial infarction in the presence of left bundle-branch block.

Sgarbossa EB et al. • N Engl J Med.. 1996;334(8):481–7. Derived from the GUSTO-1 trial.

Last Comprehensive Review: 2026-07-17

Guidelines & Evidence

Verified

Last Review: 2026-07-17

When to Use

When to Use

Evaluation of suspected Acute Myocardial Infarction (AMI) in patients with a Left Bundle Branch Block (LBBB).
To differentiate baseline LBBB ST-changes from acute ischemia.
In patients with ventricularly paced rhythms (pacemaker).

How it Works

The Rule of Discordance

In normal LBBB, the ST segment and T wave should be "discordant" (opposite) to the main QRS deflection. Sgarbossa criteria identify AMI by looking for "concordance" (ST deviation in the same direction as the QRS) or "excessive discordance."

Scoring Criteria

Concordant ST elevation ≥ 1 mm in any lead5 pts
Concordant ST depression ≥ 1 mm in lead V1, V2, or V33 pts
Discordant ST elevation ≥ 5 mm in leads with negative QRS2 pts

Interpretation

A score ≥ 3 has a specificity of ~98% for AMI, though sensitivity is low (~20-30%).

Clinical Pearls

LBBB = STEMI?

Recent ESC and AHA guidelines no longer consider "new LBBB" alone as a STEMI equivalent unless symptoms are refractory. Sgarbossa criteria help identify the subset of LBBB patients who truly have an occluded artery and need the cath lab.

Next Steps

Complementary Calculators

Modified Sgarbossa Criteria
HEART Score (Chest Pain)
GRACE ACS Risk Score
TIMI Risk Score (STEMI)
Killip Classification

The Evidence

Original Study

Electrocardiographic diagnosis of evolving acute myocardial infarction in the presence of left bundle-branch block.

Sgarbossa EB et al. • N Engl J Med.. 1996;334(8):481–7. Derived from the GUSTO-1 trial.

Last Comprehensive Review: 2026-07-17

Recent Journal Updates

CancerJul 22, 2026
Results of second‐line therapy in adult Philadelphia chromosome‐positive acute lymphoblastic leukemia

Clinical Context

We think this has broad domain relevance to Sgarbossa Criteria (MI in LBBB).

JAMAJul 21, 2026
Correction to Primary Composite Outcome in a Trial of Transfusion Strategy

Clinical Context

We think this has broad domain relevance to Sgarbossa Criteria (MI in LBBB).

British J HaematologyJul 21, 2026
Optimizing post‐transplant tyrosine kinase inhibitor maintenance in Philadelphia chromosome‐positive acute lymphoblastic leukaemia: A risk‐adapted framework

Clinical Context

We think this has broad domain relevance to Sgarbossa Criteria (MI in LBBB).