Cardiovascular Decision Support
Risk Profile Indicators
Live Score: 0
Analysis Pending
Select the patient's cardiovascular and clinical risk factors to estimate annual stroke risk and view formal guidelines.
Guidelines & Evidence
Verified
Last Review: 2026
When to Use
When to Use
Assessment of thromboembolic stroke risk in adults with non-valvular atrial fibrillation (paroxysmal, persistent, or permanent).
Decision support for initiating or withholding oral anticoagulation (OAC) therapy.
Identifying "truly low-risk" patients (Score 0 in males, Score 1 in females) who derive no net benefit from OAC.
Recalculation at each clinical encounter, as newly acquired risk factors change management.
Endorsed By
Recommended by the ESC 2020 AF Guidelines (Class I, Level A), the 2023 ACC/AHA/ACCP/HRS AF Guideline, and the European Heart Rhythm Association (EHRA). It is the global standard for AF stroke stratification.
When NOT to Use
Valvular AF (moderate-to-severe mitral stenosis or mechanical heart valve): These patients require warfarin (target INR 2–3 or 2.5–3.5) regardless of score — DOACs are contraindicated.
Hypertrophic Cardiomyopathy (HCM): HCM-related AF carries high inherent stroke risk; anticoagulate without scoring.
Cardiac Amyloidosis with AF: Consider anticoagulation even at low scores — CHA₂DS₂-VASc may underestimate risk.
Pregnancy: Anticoagulant choice (LMWH preferred) is independent of this score.
Definition of "Non-Valvular" AF
The ESC 2020 guideline redefines "non-valvular" to exclude only moderate-to-severe rheumatic mitral stenosis and prosthetic mechanical heart valves. Bioprosthetic valves, mitral valve repair, aortic stenosis, and mitral regurgitation do NOT exclude a patient from CHA₂DS₂-VASc stratification and DOAC use.
Related Scores in Practice
In clinical practice, this assessment is frequently evaluated alongside other validated measures. Depending on the patient's presentation and specific diagnostic requirements, you may also need to utilize the HAS-BLED, ORBIT Score, ABC-AF Stroke Score, ABC-AF Bleeding Score, HEMORR2HAGES, CHADS2, Creatinine Clearance Multi-Method, eGFR (CKD-EPI) or the EHRA Score to formulate a comprehensive care plan.
Last Comprehensive Review: 2026