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Cardiac Output Index

Cardiac Index (CI): Normalizes Cardiac Output (CO) to Body Surface Area (BSA).

Guidelines & Evidence

Verified

Last Review: 2026-07-17

When to Use

When to Use

Assessment of cardiac output adjusted for body size (Body Surface Area).
Essential for identifying cardiogenic shock (CI < 2.2 L/min/m2).
Monitoring response to inotropic therapy or mechanical circulatory support.

How it Works

Formula

CI = CO / BSA Where CO = Cardiac Output (L/min), BSA = Body Surface Area (m2).

Clinical Thresholds

Normal CI2.5–4.0 L/min/m2
Cardiogenic Shock< 2.2 L/min/m2
Severe Low Output< 1.8 L/min/m2

Clinical Pearls

Why indexing matters

A cardiac output of 4.0 L/min might be normal for a small elderly woman (BSA 1.5 m2, CI 2.6) but would be dangerously low for a large young man (BSA 2.2 m2, CI 1.8). Always index to BSA for clinical decision-making.

Next Steps

Complementary Calculators

Fick Cardiac Output
SVR Calculator
PVR Calculator
MAP Calculator
Stroke Volume Index

The Evidence

Hemodynamic Standards

Catheterization of the heart in man with use of a flow-directed balloon-tipped catheter.

Swan HJ et al. • N Engl J Med.. 1970;The landmark paper introducing the Swan-Ganz catheter and standardized hemodynamic indexing.

Last Comprehensive Review: 2026-07-17

Guidelines & Evidence

Verified

Last Review: 2026-07-17

When to Use

When to Use

Assessment of cardiac output adjusted for body size (Body Surface Area).
Essential for identifying cardiogenic shock (CI < 2.2 L/min/m2).
Monitoring response to inotropic therapy or mechanical circulatory support.

How it Works

Formula

CI = CO / BSA Where CO = Cardiac Output (L/min), BSA = Body Surface Area (m2).

Clinical Thresholds

Normal CI2.5–4.0 L/min/m2
Cardiogenic Shock< 2.2 L/min/m2
Severe Low Output< 1.8 L/min/m2

Clinical Pearls

Why indexing matters

A cardiac output of 4.0 L/min might be normal for a small elderly woman (BSA 1.5 m2, CI 2.6) but would be dangerously low for a large young man (BSA 2.2 m2, CI 1.8). Always index to BSA for clinical decision-making.

Next Steps

Complementary Calculators

Fick Cardiac Output
SVR Calculator
PVR Calculator
MAP Calculator
Stroke Volume Index

The Evidence

Hemodynamic Standards

Catheterization of the heart in man with use of a flow-directed balloon-tipped catheter.

Swan HJ et al. • N Engl J Med.. 1970;The landmark paper introducing the Swan-Ganz catheter and standardized hemodynamic indexing.

Last Comprehensive Review: 2026-07-17

Recent Journal Updates

JAMAJul 21, 2026
Errors in Figures

Clinical Context

We think this might be relevant to the clinical guidance for Cardiac Output Index.

WHO NewsJul 2, 2026
WHO adds first diagnostic test for Ebola Bundibugyo virus to its Emergency Use Listing

Clinical Context

We think this has broad domain relevance to Cardiac Output Index.

WHO NewsJun 15, 2026
Open letter to leaders of G7, G20, BRICS and all nations on finalizing the WHO Pandemic Agreement’s Pathogen Access and Benefit Sharing annex

Clinical Context

We think this might be relevant to the clinical guidance for Cardiac Output Index.