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Recent Journal Updates

Alzheimers & DementiaJun 7, 2026
Age‐related increase in plasma p‐tau217 in amyloid‐beta–negative cognitively unimpaired individuals affects diagnostic interpretation

Clinical Context

We think this has broad domain relevance to Killip Classification.

DiabetologiaJun 5, 2026
Early glycaemic exposure and cancer risk in people with newly diagnosed type 2 diabetes

Clinical Context

We think this has broad domain relevance to Killip Classification.

JAMAJun 2, 2026
Intra-arterial Alteplase After Thrombectomy for Acute Ischemic Stroke

Clinical Context

We think this has broad domain relevance to Killip Classification.

Killip Classification

Killip Classification: Stratifies risk of in-hospital mortality in patients with acute myocardial infarction based on clinical signs of heart failure.

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

When to Use

Routinely in the initial assessment of patients presenting with acute myocardial infarction (AMI)
To rapidly stratify risk of 30-day and in-hospital mortality based purely on bedside clinical signs
To guide intensity of care (e.g., CCU admission vs. step-down unit)

Populations

Originally validated in the pre-reperfusion era (1967), but repeatedly validated in the modern era of primary PCI and potent antithrombotic therapy. Even though overall mortality rates have fallen, the predictive gradient across the four classes remains robust.

Last Comprehensive Review: 2026

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

When to Use

Routinely in the initial assessment of patients presenting with acute myocardial infarction (AMI)
To rapidly stratify risk of 30-day and in-hospital mortality based purely on bedside clinical signs
To guide intensity of care (e.g., CCU admission vs. step-down unit)

Populations

Originally validated in the pre-reperfusion era (1967), but repeatedly validated in the modern era of primary PCI and potent antithrombotic therapy. Even though overall mortality rates have fallen, the predictive gradient across the four classes remains robust.

Last Comprehensive Review: 2026

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