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ALBI Grade (Liver)ASTCT GradingATA Thyroid RiskBCLC 2022 Staging (HCC)BSA (Mosteller)CLL-IPICML ELTS ScoreCNS-IPICTCAE v5.0Calvert FormulaDIPSS-Plus (Myelofibrosis)Deauville ScoreEAU NMIBC RiskECOG Performance StatusELN 2022 Risk (AML)ELN CML MilestonesFIGO 2021 (Ovarian)FIGO 2023 (Endometrial)FLIPI-2Fleischner 2017 GuidelinesFong Clinical Risk ScoreHCT-CI (Sorror Score)HPV/p16 OropharynxIGCCCG Risk (Testicular)IMDC (Heng) CriteriaIMWG Myeloma FrailtyIPSS-M (Molecular MDS)ISUP Grade GroupsKarnofsky Status (KPS)Khorana ScoreLugano ClassificationLung-RADS v2022MIPI-b (Biological)MRD Assessment FrameworkMSI/MMR InterpretationMayo 20/2/20 (SMM)NCCN Prostate RiskNCCN-IPI (DLBCL)NSCLC GPAOncotype DX RecurrenceOpioid EquianalgesicPD-L1 TPS InterpretationPERCIST 2.0PREDICT v3.0Platinum-Free IntervalR2-ISS (Revised 2)RANO 2.0RCB (Residual Cancer Burden)RECIST 1.1ROMA ScoreSAVER ScoreSINS ScoreSLiM-CRAB CriteriaSedlis/Peters CriteriaTNM 8th (Colorectal)TNM 8th Ed (Prognostic)TNM 9th (Nasopharynx)TNM 9th Ed (NSCLC)TNM 9th Ed (SCLC)Tyrer-Cuzick (IBIS v8)WHO 2021 CNS Class.WHO 2022 / ICC 2022 AMLZ0011 EligibilityiRECISTiwCLL 2018 ResponsemRECIST (HCC)mRENAL ScoremrTRG (Rectal MRI)
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Clinical Notice:OpiCalc is not a substitute for professional clinical judgment. Always verify dosages and guidelines.

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Recent Journal Updates

Intensive Care MedicineJun 8, 2026
International evidence-based recommendations for point-of-care lung ultrasound

Clinical Context

We think this might be relevant to the clinical guidance for ASTCT Consensus Grading (CRS & ICANS).

British J HaematologyJun 8, 2026
Real‐world application of the International Myeloma Society (IMS)/International Myeloma Working Group (IMWG) consensus on genomic staging for high‐risk multiple myeloma: A report from the Australia and New Zealand Myeloma and Related Diseases Registry

Clinical Context

We think this might be relevant to the clinical guidance for ASTCT Consensus Grading (CRS & ICANS).

DiabetologiaMay 26, 2026
Clinical and psychological phenotypes of type 1 diabetes and disordered eating derived from a case vignette series: T1DE phenotypes

Clinical Context

We think this might be relevant to the clinical guidance for ASTCT Consensus Grading (CRS & ICANS).

ASTCT Grading

ASTCT CONSENSUSCAR-T Toxicity Grading (CRS & ICANS)

Toxicity Severity

CRS Key Factors

Fever, Hypotension (BP), and Hypoxia (O2 Saturation).

ICANS Key Factors

ICE Score (orientation/writing), Level of consciousness, and Seizures.

Management Priority

STABLE MONITORING

Clinical Framing

Standard monitoring per institutional CAR-T protocol.

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

When to Use

Monitoring patients after infusion of CAR-T cells or bispecific T-cell engagers (BiTEs).
Used to determine the timing and dosage of Tocilizumab (IL-6 inhibitor) and corticosteroids.
Requires vital signs (BP, O2 sats) and the ICE (Immune Effector Cell-Associated Encephalopathy) score.

Related Scores in Practice

In clinical practice, this assessment is frequently evaluated alongside other validated measures. Depending on the patient's presentation and specific diagnostic requirements, you may also need to utilize the CTCAE v5.0, CLL-IPI or the MRD Assessment Threshold Interpreter to formulate a comprehensive care plan.

Last Comprehensive Review: 2026

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