ASTCT CONSENSUSCAR-T Toxicity Grading (CRS & ICANS)
Toxicity Severity
CRS Key Factors
Fever, Hypotension (BP), and Hypoxia (O2 Saturation).
ICANS Key Factors
ICE Score (orientation/writing), Level of consciousness, and Seizures.
Guidelines & Evidence
Verified
Last Review: 2026
Last Comprehensive Review: 2026
