OpiCalc

989 Clinical Tools

ALBI Grade (Liver)ASTCT Grading ATA Thyroid Risk BCLC 2022 Staging (HCC)BSA (Mosteller)CLL-IPI CML ELTS Score CNS-IPI CTCAE v5.0 Calvert Formula DIPSS-Plus (Myelofibrosis)Deauville Score EAU NMIBC Risk ECOG Performance Status ELN 2022 Risk (AML)ELN CML Milestones FIGO 2021 (Ovarian)FIGO 2023 (Endometrial)FLIPI-2 Fleischner 2017 Guidelines Fong Clinical Risk Score HCT-CI (Sorror Score)HPV/p16 Oropharynx IGCCCG Risk (Testicular)IMDC (Heng) Criteria IMWG Myeloma Frailty IPSS-M (Molecular MDS)ISUP Grade Groups Karnofsky Status (KPS)Khorana Score Lugano Classification Lung-RADS v2022 MIPI-b (Biological)MRD Assessment Framework MSI/MMR Interpretation Mayo 20/2/20 (SMM)NCCN Prostate Risk NCCN-IPI (DLBCL)NSCLC GPA Oncotype DX Recurrence Opioid Equianalgesic PD-L1 TPS Interpretation PERCIST 2.0 PREDICT v3.0 Platinum-Free Interval R2-ISS (Revised 2)RANO 2.0 RCB (Residual Cancer Burden)RECIST 1.1 ROMA Score SAVER Score SINS Score SLiM-CRAB Criteria Sedlis/Peters Criteria TNM 8th (Colorectal)TNM 8th Ed (Prognostic)TNM 9th (Nasopharynx)TNM 9th Ed (NSCLC)TNM 9th Ed (SCLC)Tyrer-Cuzick (IBIS v8)WHO 2021 CNS Class.WHO 2022 / ICC 2022 AML Z0011 Eligibility iRECIST iwCLL 2018 Response mRECIST (HCC)mRENAL Score mrTRG (Rectal MRI)

HPV/p16 Oropharynx

Head, Neck & CNS

HPV-positive versus HPV-negative oropharynx staging interpreter.

HPV/p16 status

T descriptor

N descriptor

M descriptor

Calculated Interpretation

Stage I

HPV-positive oropharynx uses a distinct, generally down-staged system.

Guidelines & Evidence

Clinical Details

Section 1

When to Use

Primary Use

HPV-positive versus HPV-negative oropharynx staging interpreter.

Section 2

Formula & Logic

Clinical Inputs

HPV/p16 status	Categorical selection
T descriptor	Categorical selection
N descriptor	Categorical selection
M descriptor	Categorical selection

Section 3

Pearls/Pitfalls

Result Bands

Section 4

Next Steps

Suggested Next Steps

Interpret the result in the full disease-specific clinical context.

Correlate with pathology, imaging, performance status, and multidisciplinary guidance.

Section 5

Evidence Appraisal

Evidence Base

HPV-positive versus HPV-negative oropharynx staging interpreter.

OpiCalc Medical Oncology Module • Head, Neck & CNS. 2026;Logic implemented from widely used contemporary oncology classification, prognostic, and response-assessment frameworks.

Section 6

Literature

Context

HPV/p16 Oropharynx is included in the oncology module as a structured decision-support tool for head, neck & cns workflows.

Last Comprehensive Review: 2026

Related Oncology Tools

ALBI Grade

Fong Clinical Risk Score

Have feedback about this calculator?Let us know.

HPV/p16 Oropharynx

Head, Neck & CNS

HPV-positive versus HPV-negative oropharynx staging interpreter.

HPV/p16 status

T descriptor

N descriptor

M descriptor

Calculated Interpretation

Stage I

HPV-positive oropharynx uses a distinct, generally down-staged system.

Guidelines & Evidence

Clinical Details

Section 1

When to Use

Primary Use

HPV-positive versus HPV-negative oropharynx staging interpreter.

Section 2

Formula & Logic

Clinical Inputs

HPV/p16 status	Categorical selection
T descriptor	Categorical selection
N descriptor	Categorical selection
M descriptor	Categorical selection

Section 3

Pearls/Pitfalls

Result Bands

Section 4

Next Steps

Suggested Next Steps

Interpret the result in the full disease-specific clinical context.

Correlate with pathology, imaging, performance status, and multidisciplinary guidance.

Section 5

Evidence Appraisal

Evidence Base

HPV-positive versus HPV-negative oropharynx staging interpreter.

OpiCalc Medical Oncology Module • Head, Neck & CNS. 2026;Logic implemented from widely used contemporary oncology classification, prognostic, and response-assessment frameworks.

Section 6

Literature

Context

HPV/p16 Oropharynx is included in the oncology module as a structured decision-support tool for head, neck & cns workflows.

Last Comprehensive Review: 2026

Related Oncology Tools

ALBI Grade

Fong Clinical Risk Score

Have feedback about this calculator?Let us know.