Six-factor CNS relapse risk score for aggressive B-cell lymphoma.
Calculated Interpretation
Low Risk
0 Factors
Low estimated CNS relapse risk.
Guidelines & Evidence
Clinical Details
Section 1
When to Use
Primary Use
Six-factor CNS relapse risk score for aggressive B-cell lymphoma.
Section 2
Formula & Logic
Clinical Inputs
Age > 60
Binary clinical feature
ECOG >= 2
Binary clinical feature
Stage III/IV
Binary clinical feature
LDH elevated
Binary clinical feature
>1 extranodal site
Binary clinical feature
Kidney or adrenal involvement
Binary clinical feature
Section 3
Pearls/Pitfalls
Result Bands
Section 4
Next Steps
Suggested Next Steps
01
Interpret the result in the full disease-specific clinical context.
02
Correlate with pathology, imaging, performance status, and multidisciplinary guidance.
Section 5
Evidence Appraisal
Evidence Base
Six-factor CNS relapse risk score for aggressive B-cell lymphoma.
OpiCalc Medical Oncology Module • Lymphoma. 2026;Logic implemented from widely used contemporary oncology classification, prognostic, and response-assessment frameworks.
Section 6
Literature
Context
CNS-IPI is included in the oncology module as a structured decision-support tool for lymphoma workflows.
