Z0011ACOSOG ALND Omission Eligibility
Clinical pearl
The Z0011 trial demonstrated that for women meeting these specific criteria, addition of ALND did not improve 10-year overall survival or regional recurrence-free survival, but did significantly increase morbidity (lymphedema).
Surgical Guidance
Management Strategy
Patient does not meet ACOSOG Z0011 criteria. Axillary lymph node dissection (ALND) is traditionally indicated for positive sentinel nodes.
Verified
Last Review: 2026
Giuliano AE et al. • JAMA. 2017;318(10):918-926
Last Comprehensive Review: 2026
Clinical Context
We think this might be relevant to the clinical guidance for ACOSOG Z0011 Trial Eligibility.
Clinical Context
We think this might be relevant to the clinical guidance for ACOSOG Z0011 Trial Eligibility.
Clinical Context
We think this might be relevant to the clinical guidance for ACOSOG Z0011 Trial Eligibility.