OpiCalc

989 Clinical Tools

ALBI Grade (Liver)ASTCT Grading ATA Thyroid Risk BCLC 2022 Staging (HCC)BSA (Mosteller)CLL-IPI CML ELTS Score CNS-IPI CTCAE v5.0 Calvert Formula DIPSS-Plus (Myelofibrosis)Deauville Score EAU NMIBC Risk ECOG Performance Status ELN 2022 Risk (AML)ELN CML Milestones FIGO 2021 (Ovarian)FIGO 2023 (Endometrial)FLIPI-2 Fleischner 2017 Guidelines Fong Clinical Risk Score HCT-CI (Sorror Score)HPV/p16 Oropharynx IGCCCG Risk (Testicular)IMDC (Heng) Criteria IMWG Myeloma Frailty IPSS-M (Molecular MDS)ISUP Grade Groups Karnofsky Status (KPS)Khorana Score Lugano Classification Lung-RADS v2022 MIPI-b (Biological)MRD Assessment Framework MSI/MMR Interpretation Mayo 20/2/20 (SMM)NCCN Prostate Risk NCCN-IPI (DLBCL)NSCLC GPA Oncotype DX Recurrence Opioid Equianalgesic PD-L1 TPS Interpretation PERCIST 2.0 PREDICT v3.0 Platinum-Free Interval R2-ISS (Revised 2)RANO 2.0 RCB (Residual Cancer Burden)RECIST 1.1 ROMA Score SAVER Score SINS Score SLiM-CRAB Criteria Sedlis/Peters Criteria TNM 8th (Colorectal)TNM 8th Ed (Prognostic)TNM 9th (Nasopharynx)TNM 9th Ed (NSCLC)TNM 9th Ed (SCLC)Tyrer-Cuzick (IBIS v8)WHO 2021 CNS Class.WHO 2022 / ICC 2022 AML Z0011 Eligibility iRECIST iwCLL 2018 Response mRECIST (HCC)mRENAL Score mrTRG (Rectal MRI)

RANO 2.0

Head, Neck & CNS

Unified glioma response assessment framework.

Change in measurable enhancing disease

Steroids stable or decreasing

New lesion

Clinical decline attributable to tumor

Waiting For Required Inputs

Complete the required fields to generate the oncology interpretation.

Guidelines & Evidence

Clinical Details

Section 1

When to Use

Primary Use

Unified glioma response assessment framework.

Section 2

Formula & Logic

Clinical Inputs

Change in measurable enhancing disease	%
Steroids stable or decreasing	Binary clinical feature
New lesion	Binary clinical feature
Clinical decline attributable to tumor	Binary clinical feature

Section 3

Pearls/Pitfalls

Result Bands

Section 4

Next Steps

Suggested Next Steps

Interpret the result in the full disease-specific clinical context.

Correlate with pathology, imaging, performance status, and multidisciplinary guidance.

Section 5

Evidence Appraisal

Evidence Base

Unified glioma response assessment framework.

OpiCalc Medical Oncology Module • Head, Neck & CNS. 2026;Logic implemented from widely used contemporary oncology classification, prognostic, and response-assessment frameworks.

Section 6

Literature

Context

RANO 2.0 is included in the oncology module as a structured decision-support tool for head, neck & cns workflows.

Last Comprehensive Review: 2026

Related Oncology Tools

Platinum-Free Interval

Have feedback about this calculator?Let us know.

RANO 2.0

Head, Neck & CNS

Unified glioma response assessment framework.

Change in measurable enhancing disease

Steroids stable or decreasing

New lesion

Clinical decline attributable to tumor

Waiting For Required Inputs

Complete the required fields to generate the oncology interpretation.

Guidelines & Evidence

Clinical Details

Section 1

When to Use

Primary Use

Unified glioma response assessment framework.

Section 2

Formula & Logic

Clinical Inputs

Change in measurable enhancing disease	%
Steroids stable or decreasing	Binary clinical feature
New lesion	Binary clinical feature
Clinical decline attributable to tumor	Binary clinical feature

Section 3

Pearls/Pitfalls

Result Bands

Section 4

Next Steps

Suggested Next Steps

Interpret the result in the full disease-specific clinical context.

Correlate with pathology, imaging, performance status, and multidisciplinary guidance.

Section 5

Evidence Appraisal

Evidence Base

Unified glioma response assessment framework.

OpiCalc Medical Oncology Module • Head, Neck & CNS. 2026;Logic implemented from widely used contemporary oncology classification, prognostic, and response-assessment frameworks.

Section 6

Literature

Context

RANO 2.0 is included in the oncology module as a structured decision-support tool for head, neck & cns workflows.

Last Comprehensive Review: 2026

Related Oncology Tools

Platinum-Free Interval

Have feedback about this calculator?Let us know.