Lugano staging is anchored on nodal distribution, contiguous extranodal spread, and diffuse extranodal disease.
Guidelines & Evidence
Clinical Details
Section 1
When to Use
Primary Use
PET-CT aligned staging framework for lymphoma.
Section 2
Formula & Logic
Clinical Inputs
Single nodal region or single extranodal site
Binary clinical feature
Multiple nodal regions on one side of diaphragm
Binary clinical feature
Nodal disease on both sides of diaphragm
Binary clinical feature
Contiguous extranodal extension
Binary clinical feature
Diffuse/disseminated extranodal involvement
Binary clinical feature
Section 3
Pearls/Pitfalls
Result Bands
Section 4
Next Steps
Suggested Next Steps
01
Interpret the result in the full disease-specific clinical context.
02
Correlate with pathology, imaging, performance status, and multidisciplinary guidance.
Section 5
Evidence Appraisal
Evidence Base
PET-CT aligned staging framework for lymphoma.
OpiCalc Medical Oncology Module • Lymphoma. 2026;Logic implemented from widely used contemporary oncology classification, prognostic, and response-assessment frameworks.
Section 6
Literature
Context
Lugano Classification is included in the oncology module as a structured decision-support tool for lymphoma workflows.
