Logo

OpiCalc

FavoritesSpecialtiesDrugsGuidelinesMost Used

Quick Access

Favorites
Most Used

All Specialties

OpiCalc Logo
Clinical CalculatorsDrugsGuidelines
SpecsDrugsGuides
ALBI Grade (Liver)ASTCT GradingATA Thyroid RiskBCLC 2022 Staging (HCC)BSA (Mosteller)CLL-IPICML ELTS ScoreCNS-IPICTCAE v5.0Calvert FormulaDIPSS-Plus (Myelofibrosis)Deauville ScoreEAU NMIBC RiskECOG Performance StatusELN 2022 Risk (AML)ELN CML MilestonesFIGO 2021 (Ovarian)FIGO 2023 (Endometrial)FLIPI-2Fleischner 2017 GuidelinesFong Clinical Risk ScoreHCT-CI (Sorror Score)HPV/p16 OropharynxIGCCCG Risk (Testicular)IMDC (Heng) CriteriaIMWG Myeloma FrailtyIPSS-M (Molecular MDS)ISUP Grade GroupsKarnofsky Status (KPS)Khorana ScoreLugano ClassificationLung-RADS v2022MIPI-b (Biological)MRD Assessment FrameworkMSI/MMR InterpretationMayo 20/2/20 (SMM)NCCN Prostate RiskNCCN-IPI (DLBCL)NSCLC GPAOncotype DX RecurrenceOpioid EquianalgesicPD-L1 TPS InterpretationPERCIST 2.0PREDICT v3.0Platinum-Free IntervalR2-ISS (Revised 2)RANO 2.0RCB (Residual Cancer Burden)RECIST 1.1ROMA ScoreSAVER ScoreSINS ScoreSLiM-CRAB CriteriaSedlis/Peters CriteriaTNM 8th (Colorectal)TNM 8th Ed (Prognostic)TNM 9th (Nasopharynx)TNM 9th Ed (NSCLC)TNM 9th Ed (SCLC)Tyrer-Cuzick (IBIS v8)WHO 2021 CNS Class.WHO 2022 / ICC 2022 AMLZ0011 EligibilityiRECISTiwCLL 2018 ResponsemRECIST (HCC)mRENAL ScoremrTRG (Rectal MRI)
OpiCalc Logo

OpiCalc

Easy, fast, and private medical tools for clinicians. Always free.

No Login Required
Ready for the Bedside

Resources

About UsEditorial PolicyMedical DisclaimerPrivacy PolicyTerms of UseCookie Policy

Support

Contact Us

Clinical Notice:OpiCalc is not a substitute for professional clinical judgment. Always verify dosages and guidelines.

OpiCalc © 2026

•

All Rights Reserved

ATA Thyroid Risk

ATA THYROIDRisk Stratification for Differentiated Cancer

Clinical Risk Tier

Note: ATA risk is distinct from AJCC staging. ATA risk predicts the likelihood of recurrence, while AJCC predicts the likelihood of mortality.

Risk Profile

Low

Recurrence Outlook

Low risk of structural recurrence (< 5%). Routine follow-up with thyroglobulin monitoring is standard.

Guidelines & Evidence

Verified

Last Review: 2026

When to Use

Clinical Use

Patients with papillary or follicular thyroid cancer after total thyroidectomy.
Used to determine the necessity and dosage of Radioactive Iodine (RAI) ablation.
Guides the intensity of follow-up (frequency of ultrasound and thyroglobulin monitoring).

How it Works

ATA Risk Categories

CategoryTypical Findings
Low RiskIntrathyroidal tumor, < 5 nodes (all < 2mm), no vascular invasion.
Intermediate RiskMicroscopic ETE, vascular invasion, or > 5 nodes (all < 3cm).
High RiskGross ETE, incomplete resection, distant metastases, or bulky nodes (≥ 3cm).

Clinical Pearls

Recurrence Probability

CategoryRisk of Structural Recurrence
Low Risk< 5%
Intermediate Risk10 - 20%
High Risk30 - 55%

Management Pearl

Low-risk patients do NOT routinely require RAI, as it does not improve their already excellent prognosis. High-risk patients should always receive adjuvant RAI (typically 100-150 mCi) to eradicate microscopic residual disease.

The Evidence

Key Reference

2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer

Haugen BR et al. • Thyroid. 2016;26(1):1-133

Last Comprehensive Review: 2026

Related Tools

CTCAE v5.0
Oncology CalculatorsInternal Medicine CalculatorsEmergency Medicine Calculators
Have feedback about this calculator?Let us know.

Recent Journal Updates

CancerJul 23, 2026
Outcomes of loncastuximab tesirine in heavily pretreated patients with diffuse large B‐cell lymphoma, including the post‐CAR T‐cell therapy setting: A meta‐analysis

Clinical Context

We think this has broad domain relevance to ATA Thyroid Recurrence Risk.

CancerJul 22, 2026
Maura L. Gillison, MD, PhD (1965–2026): A visionary trailblazer who transformed how we understand head and neck cancers, while mentoring and caring for many

Clinical Context

We think this has broad domain relevance to ATA Thyroid Recurrence Risk.

WHO NewsJun 23, 2026
WHO urges scale up of newborn screening to improve early detection and care of birth defects

Clinical Context

We think this might be relevant to the clinical guidance for ATA Thyroid Recurrence Risk.