ROMA SCORERisk of Ovarian Malignancy Algorithm
Clinical & Lab Inputs
pmol/L
U/mL
Clinical pearl
HE4 is less affected by endometriosis or inflammatory conditions compared to CA-125, making the ROMA score more specific than CA-125 alone for detecting epithelial ovarian cancer.
Guidelines & Evidence
Verified
Last Review: 2026
Last Comprehensive Review: 2026
