ITP Bleeding Score

ITP-BAT SMO Score: Quantifying bleeding in ITP. Mucosal (M) and Organ (O) bleeding are higher priority than Skin (S) manifestations.

Skin (S) score

Mucosa (M) score

Organ (O) score

Includes GI, CNS, Pulmonary, GU

Composite Bleeding Profile

S0 M0 O0

Dry Purpura / Low Risk

Bleeding risk is clinically low. Management depends on baseline platelet count and trend.

Guidelines & Evidence

Verified

Last Review: 2026-07-17

When to Use

Standardized scoring of bleeding severity in patients with Immune Thrombocytopenia (ITP).

To guide treatment initiation (targeting the "Bleeding" rather than just the "Number").

Symmetry of reporting for clinical trials in ITP.

Patient Population

Adult and pediatric patients with diagnosed ITP and low platelet counts.

How it Works

Organ Domains (0–4)

Domain	Grade 0	Grade 4 (Severe)
Skin (S)	None	Large hematomas, extensive bruising
Mucosa (M)	None	Active bleeding requiring intervention (e.g. packing)
Organs (O)	None	CNS, Pulmonary, or Massive GI hemorrhage

Interpretation

The SMO score (e.g., S2, M1, O0) provides a rapid phenotype. A score of ≥ 2 in Mucosa or ≥ 1 in Organs typically warrants immediate systemic therapy (IVIG/Steroids) regardless of the platelet count.

Last Comprehensive Review: 2026-07-17

Recent Journal Updates

PLOS MedicineJul 23, 2026

Exploring parental prenatal influences on child health: A multicohort study and data visualisation tool

Clinical Context

We think this might be relevant to the clinical guidance for ITP Bleeding Assessment Tool (ITP-BAT).

British J Clinical PharmacologyJul 21, 2026

A university‐certified course on dossier assessment for regulatory scientists in Africa—Reporting on our 5‐year experience

Clinical Context

We think this might be relevant to the clinical guidance for ITP Bleeding Assessment Tool (ITP-BAT).

British J HaematologyJul 17, 2026

In a nutshell: Explaining joint and muscle bleeding in individuals with haemophilia A and B

Clinical Context

We think this might be relevant to the clinical guidance for ITP Bleeding Assessment Tool (ITP-BAT).

ITP Bleeding Score

Skin (S) score

Mucosa (M) score

Organ (O) score

S0 M0 O0

When to Use

When to Use

Patient Population

How it Works

Organ Domains (0–4)

Interpretation

Clinical Pearls

Treat the Patient, Not the Number

The Evidence

Primary Consensus

Standardization of bleeding assessment in immune thrombocytopenia: report from the International Working Group.

Origins & History

Evolution

Recent Journal Updates

ITP Bleeding Score

Skin (S) score

Mucosa (M) score

Organ (O) score

S0 M0 O0

When to Use

When to Use

Patient Population

How it Works

Organ Domains (0–4)

Interpretation

Clinical Pearls

Treat the Patient, Not the Number

The Evidence

Primary Consensus

Standardization of bleeding assessment in immune thrombocytopenia: report from the International Working Group.

Origins & History

Evolution

Recent Journal Updates