Sokal/EUTOS/ELTS Comparison

The older Sokal score tends to over-categorize patients into high-risk groups. The ELTS score, derived from a cohort of >2,000 TKI-treated patients, provides a more accurate estimate of the small percentage of patients likely to die from CML progression.

High ELTS/Sokal scores often prompt clinicians to consider stronger initial therapy (e.g., Dasatinib or Nilotinib) to achieve faster molecular responses.

ELTS stands for European LeukemiaNet (ELN) Treatment Outcome Study.