Vienna Prediction Model

Vienna Recurrence Model: Validated for both sexes. Requires D-dimer measured ~3 weeks AFTER stopping anticoagulation. 12-month risk > 5% generally favors long-term therapy.

1. Biological Sex

2. Index VTE Site

3. Post-Anticoagulation D-dimer

µg/L (FEU)

Awaiting D-dimer

Guidelines & Evidence

Verified

Last Review: 2026-07-17

When to Use

Predicting the risk of recurrence in patients with a first unprovoked Venous Thromboembolism (VTE).

Applying to both men and women (unlike the HERDOO2 rule).

Aiding the decision to discontinue anticoagulation after the initial 3–6 month treatment period.

Inclusion Criteria

Patients with a first unprovoked DVT (proximal or distal) or Pulmonary Embolism (PE).

How it Works

Variables (Vienna Points)

Factor	Clinical significance
Biological Sex	Men carry a ~2-fold higher risk than women.
VTE Location	Proximal DVT/PE carries higher risk than distal/isolated DVT.
D-dimer Level	Measured 3 weeks after stopping anticoagulation.

The NOMOGRAM Logic

The model utilizes a Cox proportional hazards regression. A cumulative risk of < 5% at 1 year is often used as the threshold for safe discontinuation.

Last Comprehensive Review: 2026-07-17

Recent Journal Updates

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Clinical Context

We think this might be relevant to the clinical guidance for Vienna Prediction Model (VTE Recurrence).

Vienna Prediction Model

When to Use

When to Use

Inclusion Criteria

How it Works

Variables (Vienna Points)

The NOMOGRAM Logic

Clinical Pearls

D-dimer Variability

Distal DVT Escape

The Evidence

Primary Strategy

The Vienna Prediction Model for identifying patients with a low risk of recurrent venous thromboembolism.

Origins & History

Development

Recent Journal Updates

Vienna Prediction Model

When to Use

When to Use

Inclusion Criteria

How it Works

Variables (Vienna Points)

The NOMOGRAM Logic

Clinical Pearls

D-dimer Variability

Distal DVT Escape

The Evidence

Primary Strategy

The Vienna Prediction Model for identifying patients with a low risk of recurrent venous thromboembolism.

Origins & History

Development

Recent Journal Updates