VWD Panel Triage: The ratio of Activity (RCo) to Antigen (Ag) is the primary engine for differentiating quantitative (Type 1) from qualitative (Type 2) defects.
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Last Review: 2026-07-17
| Type | VWF:Ag | VWF:RCo | Ratio (RCo/Ag) | Description |
|---|---|---|---|---|
| Type 1 | Low (< 30-50%) | Low | > 0.6 | Partial quantitative deficiency. |
| Type 2 | Low or Normal | Very Low | < 0.6 | Qualitative functional defect. |
| Type 3 | Absent (< 5%) | Absent | N/A | Severe total deficiency. |
James PD et al. • Blood Advances. 2021;Current international gold standard.
View SourceLast Comprehensive Review: 2026-07-17
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